Thermotropic phase behaviour of the pseudobinary mixtures of DPPC/C12E5 and DMPC/C12E5 determined by differential scanning calorimetry and ultrasonic velocimetry

Thermodynamic and structural behaviour of equimolar POPC/CnE4 (n=8, 12, 16) mixtures by sorption gravimetry, 2H NMR spectroscopy and X-ray diffraction

“…Due to their surfactant nature, C n E m destabilise the lipid bilayer and tend to solubilise membrane components (Heerklotz et al, 1994;Mädler et al, 1994;Pfeiffer et al, 2006). Therefore, the information on the lyotropic phase state, usually obtained by diffraction or spectroscopic methods (Winter et al, 1998) is substantial for the interpretation of results derived from non-structural methods.…”

Phase Transitions of Binary Lipid Mixtures: A Combined Study by Adiabatic Scanning Calorimetry and Quartz Crystal Microbalance with Dissipation Monitoring

“…This requires the knowledge of static and kinetic thermodynamic properties of pure lipids and lipid mixtures. Characterization and mapping of phase diagrams have been carried out for lipid dispersions using several techniques such as differential scanning calorimetry (DSC) [9], nuclear magnetic resonance (NMR) [10], X-ray scattering [11], fluorescence microscopy [12], laser ultrasonics [13], and ultrasonic velocimetry [14]. Nevertheless, the transition temperatures are usually determined with a large uncertainty due to the typically broad transitions and the limited sensitivity of the experimental setups.…”

Inhomogeneities in sodium decylsulfate doped 1,2-dipalmitoylphosphatidylcholine bilayer

“…The presence of composition inhomogeneities could also be induced by some surfactants, as shown by Pfeiffer et al [38] who detected overall concentration conditions for which different domains with constant local surfactant concentration were present. Heerklotz [39] provided strong evidence that the nonionic surfactant Triton can induce domains formation.…”