Three-dimensional analysis of acetabular orientation using a semi-automated algorithm

Lee, Changhwan; Jang, Ji Hye; Kim, Hyung Wook; Kim, Young Soo; Kim, Yeesuk

doi:10.1080/24699322.2018.1545872

Cited by 9 publications

(8 citation statements)

References 23 publications

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“…Our data for the anatomical mean acetabular anteversion of 19.4° and an acetabular inclination of 49.6° are in the range of those reported in the literature [ 17 , 20 , 21 ]. Cup misplacement in THA with increased or reduced anteversion or inclination may result in an increased risk of dislocation and implant wear, therefore, acetabular orientation needs to be assessed for THA [ 22 ].…”

Section: Discussionsupporting

confidence: 79%

Lumbosacral Transitional Vertebrae Influence on Acetabular Orientation and Pelvic Tilt

Becker

Taheri

Haffer

et al. 2022

JCM

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Lumbosacral transitional vertebrae (LSTV) are common congenital variances with a prevalence found in the population up to 35.6%. The literature demonstrates an influence of LSTV on bony pelvic anatomy. The influence on the anatomical acetabular orientation, which is important for cup positioning in total hip arthroplasty, has not yet been described for patients with LSTV. A total of 53 patients with LSTV were identified from a CT Database including 819 subjects. Fifty patients with LSTV could be included and were matched for age and sex against a control group. We examined the influence of LSTV, classified according to Castellvi, on acetabular orientation and pelvic tilt in the supine position. Functional acetabular anteversion and inclination, assessed against the table plane, were compared against anatomical acetabular anteversion and inclination, assessed against the anterior pelvic plane. The anatomical acetabular inclination correlated with the pelvic tilt (r = 0.363, p < 0.001). The anatomical acetabular inclination was significantly larger than the functional acetabular inclination in the supine position (p < 0.001). Castellvi grading of LSTV correlated negatively with pelvic tilt (ρ = −0.387, p = 0.006). Castellvi grading correlated significantly with functional acetabular anteversion (ρ = 0.324, p = 0.022) and anatomical acetabular anteversion (ρ = 0.306, p = 0.022). A higher Castellvi grading was accompanied by a reduced pelvic tilt in the supine position. The functional acetabular anteversion and anatomical acetabular anteversion increased in parallel to the higher Castellvi grading. Therefore, LSTV and Castellvi grading might be assessed on pre-operative X-rays prior to hip arthroplasty and surgeons might consider adjusting cup positioning accordingly.

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Section: Discussionsupporting

confidence: 79%

Lumbosacral Transitional Vertebrae Influence on Acetabular Orientation and Pelvic Tilt

Becker

Taheri

Haffer

et al. 2022

JCM

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“…The scanner indexes were set at a current of 177 μA, a voltage of 45 kVp, and a voxel size of 15.6 μm. Three-dimensional (3D) analysis of acetabular orientation used a semiautomated algorithm ( 50 ). The volume of acetabular fossa was determined according to region of interest (ROI) using ImageJ freeware by measuring the edge of the acetabulum and femoral head ( 51 ).…”

Section: Methodsmentioning

confidence: 99%

Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy

Yan

Zheng

et al. 2022

Proc. Natl. Acad. Sci. U.S.A.

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Developmental dysplasia of the hip (DDH) is one of the most common congenital skeletal malformations; however, its etiology remains unclear. Here, we conducted whole-exome sequencing in eight DDH families followed by targeted sequencing of 68 sporadic DDH patients. We identified likely pathogenic variants in the LRP1 (low-density lipoprotein receptor-related protein 1) gene in two families and seven unrelated patients. All patients harboring the LRP1 variants presented a typical DDH phenotype. The heterozygous Lrp1 knockout (KO) mouse ( Lrp1 +/− ) showed phenotypes recapitulating the human DDH phenotypes, indicating Lrp1 loss of function causes DDH. Lrp1 knockin mice with a missense variant corresponding to a human variant identified in DDH ( Lrp1 R1783W ) also presented DDH phenotypes, which were milder in heterozygotes and severer in homozygotes than those of the Lrp1 KO mouse. The timing of triradiate cartilage development was brought forward 1 or 2 wk earlier in the LRP-deficient mice, which leads to malformation of the acetabulum and femoral head. Furthermore, Lrp1 deficiency caused a significant decrease of chondrogenic ability in vitro. During the chondrogenic induction of mice bone marrow stem cells and ATDC5 (an inducible chondrogenic cell line), Lrp1 deficiency caused decreased autophagy levels with significant β-catenin up-regulation and suppression of chondrocyte marker genes. The expression of chondrocyte markers was rescued by PNU-74654 (a β-catenin antagonist) in an shRNA-Lrp1–expressed ATDC5 cell. Our study reveals a critical role of LRP1 in the etiology and pathogenesis of DDH, opening an avenue for its treatment.

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“…In the coronal and axial plane passing through the midpoint, acetabular length, height, width, and depth were measured to determine the acetabular size in the control and Crowe IV DDH group. According to the acetabular rim, the acetabular volume was also evaluated with reference to the acetabular opening plane (18,19) (Figure 1C-1E).…”

Section: D Reconstruction and Acetabular Size Analysismentioning

confidence: 99%

Three-dimensional morphological analysis of true acetabulum in Crowe type IV hip dysplasia via standard-sized cup-simulated implantation

Yang¹,

Ma²,

Li³

et al. 2022

Quant Imaging Med Surg

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Background and Objective: Acetabular reconstruction in Crowe type IV developmental dysplasia of the hip (DDH) can be a challenging procedure for surgeons. A high risk of acetabular revision has been reported to be associated with extremely small acetabular prostheses. However, to our knowledge, quantitative morphological and coverage evaluations of the true acetabulum in Crowe IV hips have been infrequently conducted. Useful bony landmarks for acetabular reconstruction can also facilitate satisfactory intraoperative implantation. The aim of the present study was to investigate the anatomical size, orientation angles, and 2/3-dimensional (2D/3D) coverage parameters of the true acetabulum in Crowe IV hips; evaluate the feasibility of standard cup (>44 mm) implantation at the true acetabulum in Crowe IV hips; and identify the optimal position and useful bony landmarks of the acetabular reaming center in Crowe IV hips.Methods: A total of 42 Crowe IV hips in 37 patients and 36 normal hips were included in this study. Based on pelvic 3D computed tomography (CT) reconstruction, anatomical size and integral volume of the true acetabulum were measured quantitatively. Through standard-size cup-simulated implantation, morphological assessments of the true acetabulum included Cup-CE, Cup-Sharp, acetabular anteversion angle, and thickness of the medial wall.Acetabular sector angles (ASAs) and the component coverage ratio were measured to provide coverage indices.Acetabular reconstruction was also performed at different vertical levels to measure medial bone stock and 3D component coverage. Bony landmarks for optimal component center location were also determined.Results: The anatomic shape and volume of the acetabular triangle were significantly smaller in Crowe IV hips. Compared with the control group, the dysplastic acetabulum was more anteverted and abductive, with a thicker medial wall. According to the true acetabulum, bone stock was relatively sufficient in the posterior direction and prominently deficient in the anterosuperior and superior direction. The average 3D component coverage reached 79.89% by standard-sized cup implantation, with the most satisfactory coverage achieved at the true acetabulum (at the level of 13.32 mm above the transverse acetabular ligament).

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Three-dimensional analysis of acetabular orientation using a semi-automated algorithm

Cited by 9 publications

References 23 publications

Lumbosacral Transitional Vertebrae Influence on Acetabular Orientation and Pelvic Tilt

Lumbosacral Transitional Vertebrae Influence on Acetabular Orientation and Pelvic Tilt

Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy

Three-dimensional morphological analysis of true acetabulum in Crowe type IV hip dysplasia via standard-sized cup-simulated implantation

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