Three-dimensional conformal radiation therapy for refractory laryngeal granuloma

Wang, Jianhua; Shi, Mei; Xia, Yunlong; Luo, Shanquan; Fu, Xuehai; Xiao, Feng; Li, Jianping; Deng, Zhihong; Long, Xiaoli

doi:10.1177/030089161109700315

Cited by 4 publications

(2 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Le traitement conventionnel consiste en une exérèse chirurgicale par bistouri ou laser [13], [14]. Des approches plus conservatives ciblant les facteurs favorisants comme un traitement antireflux et une thérapie vocale sont également prescrites.…”

Section: Discussionunclassified

Postintubation granuloma, a complication to recognize: a case report

Montigny

Daoudia

Fassnacht

et al. 2011

Ann. Fr. Med. Urgence

View full text Add to dashboard Cite

Section: Discussionunclassified

Postintubation granuloma, a complication to recognize: a case report

Montigny

Daoudia

Fassnacht

et al. 2011

Ann. Fr. Med. Urgence

View full text Add to dashboard Cite

“…Авторы рекомендуют иметь в виду возможность радиоте-рапии у пациентов с гранулемами гортани в случае неэф-фективности всех остальных методов лечения. При этом использование низких доз излучения позволяет миними-зировать ранние и отсроченные побочные эффекты, в том числе избежать озлокачествления [31].…”

unclassified

Treatment Experience of Patients With Laryngeal Granuloma Using High-Energy Surgical Equipment Ent

2017

View full text Add to dashboard Cite

Гранулемы в зоне голосового отростка черпаловидного хряща (контактные) развиваются вследствие микротравмы, хро-нического кашля, гастроэзофагеального рефлюкса, перенапряжения голоса и психосоматических особенностей. В статье приведены данные обзора литературы по проблеме лечения гранулем гортани: хирургическое лечение показано при неэффективности консервативного лечения, а также при наличии образований, стенозирующих просвет гортани и требу-ющих морфологической верификации. В Клинике болезней уха, горла и носа Первого МГМУ им. И.М. Сеченова с 2014 по 2017 г. наблюдалось 8 пациентов: одна пациентка с постинтубационными гранулемами успешно прооперирована, реци-дива нет в течение 6 месяцев. Семь пациентов проходят лечение по поводу гастроэзофагеальной рефлюксной болезни, на фоне чего в одном случае отмечен полный регресс гранулемы; пяти больным проведено хирургическое удаление грану-лемы, из них у трех не было рецидива, а у двух отмечено повторное появление гранулем спустя 6 месяцев, по поводу чего они реоперированы. Интраоперационное применение радиоволнового аппарата при удалении гранулемы с последующей коагуляцией места ее прикрепления очевидно уменьшает риск рецидива. bothsides granuloma underwent a surgical excision under general anesthesia, followed up for 6 months and had no recurrence. 7 patients (6 males and 1 female) were treated with proton pump inhibitors due to they had gastroesophageal reflux disease. In 1 case contact granuloma reduced after 3 month conservative therapy without recurrence. One patient was non compliant. In 5 others microsurgical treatment performed. 2 of them had recurrent granuloma after 6 months and underwent repeated microsurgical excision using radiofrequency ablation. According the world and our own experience high-energy surgical equipment is recommended to be used in recurrent laryngeal granuloma to reduce it's recurrence rate.

show abstract

Surgery and proton pump inhibitors for treatment of vocal process granulomas

Duan

He-Juan

Zheng

et al. 2013

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

The aim of this study was to analyze the outcomes of vocal process granulomas treated with surgery and proton pump inhibitors and to specify related factors of recurrence. The medical records of patients with diagnosis of vocal process granuloma between 2000 and 2012 were reviewed. All patients were treated with surgery and proton pump inhibitors for at least 1 month. Forty-one patients were reviewed; mean follow-up time was 45 months. There was no recurrence among the patients who had a recent history of intubation. The recurrence rates of contact granuloma was 38.7 %, and significantly related to the frequency of surgery (P = 0.042), but was not significantly associated with the history of acid reflux (P = 0.676) and vocal abuse (P = 0.447), lesion size (P = 0.203) or surgical techniques (P = 0.331). Surgery combined with proton pump inhibitors was partially effective for the vocal process granulomas, especially with intubated patients. However, repeat surgery for recurrent contact granuloma should be preceded with caution due to high recurrence rates.

show abstract

Three-dimensional conformal radiation therapy for refractory laryngeal granuloma

Abstract: 3DCRT is a safe and effective therapy for refractory laryngeal granulomas, especially when other methods have failed.

Cited by 4 publications

References 28 publications

Postintubation granuloma, a complication to recognize: a case report

Postintubation granuloma, a complication to recognize: a case report

Treatment Experience of Patients With Laryngeal Granuloma Using High-Energy Surgical Equipment Ent

Surgery and proton pump inhibitors for treatment of vocal process granulomas

Contact Info

Product

Resources

About