Three dimensional electrochemical system for neurobiological studies

Abstract

Abstract-In this work we report a novel three dimensional electrode array for electrochemical measurements in neuronal studies. The main advantage of working with these out-of-plane structures is the enhanced sensitivity of the system in terms of measuring electrochemical changes in the environment of a cell culture in real time. In addition, the system is devised to offer a compact solution that helps to obtain a homogeneous distribution of current density among the active electrodes.

Fabrication and Characterization of 3D Micro- and Nanoelectrodes for Neuron Recordings

“…The metallization in reality is not as good, as is shown schematically in step 8 in Figure 1 , as the steepest places on the electrodes are not covered with metal or are only covered by a thin layer [ 25 , 26 ]. That is why the doped silicon is required; to secure a conductive path to the top of the electrodes.…”