Three-dimensional saline infusion sonography compared to two-dimensional saline infusion sonography for the diagnosis of focal intracavitary lesions

Objective To assess three‐dimensional (3D) ultrasound combined with power Doppler (PD) for the differential diagnosis of endometrial lesions among infertile women. Methods A prospective study carried out at a reproductive medicine center in Luoyang, China, between January and December 2015. The inclusion criteria were asymptomatic infertility with normal endometrium or specific endometrial lesions. Participants were subdivided by whether they had normal endometrium (group 1, n=357), or endometrial lesions including polyps, hyperplasia, intrauterine adhesions, or endometritis (group 2, n=99). 3D PD and hysteroscopy were performed in the follicular phase. Endometrial thickness, volume, vascularization index (VI), flow index (FI), and vascularization flow index (VFI), and subendometrial VI, FI, and VFI were calculated. Endometrial lesions were confirmed by pathologic analysis. Results The overall prevalence of endometrial lesions was 99/456 (21.3%). Endometrial thickness and volume were significantly larger in group 2 than in group 1 (9.96 ± 3.24 vs 8.15 ± 2.50 mm and 3.70 ± 2.54 vs 2.42 ± 1.64 cm3, respectively; both P<0.001). Endometrial thickness and volume were larger among women with endometrial polyps and hyperplasia; endometrial VI, FI, and VFI were lower among women with intrauterine adhesions. Conclusion Three‐dimensional PD has value for the differential diagnosis of endometrial lesions among infertile women. Clinical trial registration The trial is registered in the Chinese Clinical Trial Registry as ChiCTR1800015799.

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“…Few studies have used 3D PD to assess endometrial and subendometrial vascularization during the evaluation of endometrial lesions . Cil et al .…”

Section: Discussionmentioning

confidence: 99%

“…Few studies have used 3D PD to assess endometrial and subendometrial vascularization during the evaluation of endometrial lesions. 6,12 Cil et al 6 reported that a single-vessel pattern was characteristic of endometrial polyps, whereas a rim-like vessel pattern was typical of a submucosal fibroid. However, those indicators were subjective.…”

Section: Discussionmentioning

confidence: 99%

Three‐dimensional 3D ultrasound combined with power Doppler for the differential diagnosis of endometrial lesions among infertile women

Han

Liang

et al. 2019

Intl J Gynecology & Obste

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“…However, there were some limitations of the instrument when used with patients whose symptoms were caused by endometrial polyp or submucous leiomyoma. Nowadays, there are minimally invasive alternative methods used to detect endometrial polyp or submucous leiomyoma, such as three-dimensional saline infusion sonography (3D SIS) (Nieuwenhuis et al, 2017) and office hysteroscopy.…”

Section: Discussionmentioning

confidence: 99%

Histological Sampling of Endometrial Tissue: Comparison between the MedGyn® Endosampler and Formal Fractional Curettage in Patients with Abnormal Uterine Bleeding

Tumrongkunagon¹,

Suknikhom²

2019

Asian Pac J Cancer Prev

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Background: Several methods have been used for evaluation of the endometrial pathology in patients with abnormal uterine bleeding. Endometrial biopsy is one of the primary methods used for diagnostic evaluation, which is a minimally invasive approach. The aim of this study was to compare the adequacy yield of samples obtained by MedGyn® Endosampler with Formal Fractional Curettage. Objective: This study was designed to compare the endometrial tissue quality and diagnostic accuracy between MedGyn® Endosampler and Formal Fractional Curettage in patients with abnormal uterine bleeding. Methods: A total of 85 endometrial tissue samples were tested by the MedGyn® Endosampler, followed by Formal Fractional Curettage, from patients at Phrapokklao Hospital who were eligible for the study and met the inclusion criteria for uterine curettage. Samples were collected between August, 2018 and April, 2019. Both operations were performed by the same investigator. The samples were submitted separately and sent to the same pathologist. Results: The mean age of the patients was 46.92 ± 6.94 years. 91.76% (78/85) of the samples obtained by Formal Fractional Curettage and 89.41% (76/85) of the samples obtained by MedGyn® Endosampler device were adequate for histopathological examination. The difference was not statistically significant (p = 0.317). The pathological results of endometrial tissue from both techniques were the same in 67 patients (78.82%) and different in 14 patients (16.47%). MedGyn® Endosampler was six times more cost effective when compared to Formal Fractional Curettage. Conclusions: Endometrial sampling using MedGyn® Endosampler is a safe, adequate, accurate, cost effective outpatient procedure which precludes general anesthesia. Therefore, it could be an alternative method for endometrial sampling.

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“…Moreover, 2D and 3D-SIS are useful in the diagnosis of diseases closely related to infertility, in particular myomas, endometrial polyps and Asherman's syndrome [14,15]. It allows the preoperative evaluation of benign intracavitary lesions [16]. Sonohysterography also plays an important role in secondary fertility investigation due to cesarian scar pregnancy.…”

Section: Sonohysterographymentioning

confidence: 99%

A comprehensive use of ultrasound examination in infertility workup

Kowalczyk

Klimek

et al. 2021

Ginekol Pol

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Three-dimensional saline infusion sonography compared to two-dimensional saline infusion sonography for the diagnosis of focal intracavitary lesions

Cited by 19 publications

References 61 publications

Three‐dimensional 3D ultrasound combined with power Doppler for the differential diagnosis of endometrial lesions among infertile women

Three‐dimensional 3D ultrasound combined with power Doppler for the differential diagnosis of endometrial lesions among infertile women

Histological Sampling of Endometrial Tissue: Comparison between the MedGyn® Endosampler and Formal Fractional Curettage in Patients with Abnormal Uterine Bleeding

A comprehensive use of ultrasound examination in infertility workup

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