Three-dimensional spectral-domain optical coherence tomography of melanocytoma of the optic nerve head

Clinical and Spectral-Domain Optical Coherence Tomography Appearance of Optic Disc Melanocytoma: A New Classification and Differentiation from Pigmented Choroidal Lesions

“…The SD-OCT findings of melanoma and nevus we observed were consistent with previous large series [5,6,7,8,9,10,11,12,13,14,15,16,17,18,19]. The heavily pigmented Type 1 optic disc melanocytoma is usually distinguishable from choroidal melanoma and choroidal nevus by funduscopic findings, but SD-OCT may help confirm the diagnosis and identify associated features, such as subretinal fluid, that could affect the clinical course.…”

“…These are summarized in Table 3[5,6,7,8,9,10,11,12,13,14,15,16,17,18,19]. Our cases corroborate a constellation of findings that have previously been reported and that are typical of most heavily pigmented optic disc melanocytomas: a very prominent and dense optical shadowing by the heavily pigmented tumor; a sharply demarcated interface between the tumor and a thin, hyperreflective layer of the disorganized overlying retina, and hyperreflective dots accumulated at the tumor-retina interface.…”

“…The SD-OCT features of choroidal melanoma and nevus have been well described [1,2,3,4]. While a number of case reports and small case series include limited descriptions of the corresponding features of the classic, darkly pigmented optic disc melanocytoma, these have not included the uncommon, more lightly pigmented form of the tumor [5,6,7,8,9,10,11,12,13,14,15,16,17,18,19]. We compared the features of both the classic, darkly pigmented and the atypical, more lightly pigmented optic disc melanocytoma with those of pigmented choroidal lesions.…”

Multimodal imaging of optic disc melanocytoma

“…Choroidal involvement is suggested by the presence of a hyperreflective area within the choroid associated with an upward displacement of the normal retinal pigment epithelium (RPE) architecture. 11,15,16 EDI-OCT and SS-OCT allowed clinicians to examine the choroid (a, b, c, d) images scanned over an area of 3 mm × 3 mm: on the left the infrared images, in the middle the whole scans, on the right the choriocapillaris slabs. In all cases we observed blood vessels network intrinsic to the tumor mass; vessels were heterogeneously distributed within the lesions, with some more prominent irregular vessels and attenuated signals areas due to vasculature absence or obscuration by the tumor tissue.…”