Three‐Dimensionally Printed Biphasic Calcium Phosphate Ceramic Substrates as the Sole Inducer of Osteogenic Differentiation in Stromal Vascular Fraction Cells
Louis Brochet,
Céline Thomann,
Carlos Chocarro‐Wrona
et al.
Abstract:The stromal vascular fraction (SVF) is a derivate of fat tissue comprising both adipose‐derived mesenchymal stem cells and endothelial cells and serves as a promising cell source for engineering vascularized bone tissues. Its combination with osteoconductive biphasic calcium phosphate (BCP) ceramic may represent a point‐of‐care agent for bone reconstruction. Here we assessed the proliferation and osteogenic differentiation capacities of SVF on 3D printed BCP implants, in comparison with isolated adipose‐derive… Show more
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