Thrombectomy and Thrombolysis

Dunn, Marilyn; Weisse, Chick

doi:10.1002/9781118910924.ch47

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Medical therapy is often recommended in ambulatory dogs with chronic thrombi, whereas procedural intervention is more commonly considered in acute non‐ambulatory dogs with life‐threatening loss of limb perfusion. 1 , 3 , 12 …”

Section: Introductionmentioning

confidence: 99%

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Stenting of the caudal aorta and aortic trifurcation for the treatment of thrombosis in 7 dogs

Gavin¹,

Weisse

Berent

2022

Veterinary Internal Medicne

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Background Aortic and aortoiliac thrombosis in dogs causes disease and death. Objective To describe the procedure and outcomes for stenting the caudal aorta and aortoiliac trifurcation. Animals Seven client‐owned dogs that underwent aortic/aortoiliac stenting for treatment of thrombosis. Methods Retrospective multi‐center investigation. Medical records were reviewed for dogs that underwent stenting of the aorta or aortoiliac trifurcation between 2008 and 2020. Information collected included history, signalment, clinicopathologic data, diagnostic imaging, procedure reports, and outcomes. Results Seven dogs with an occlusive thrombus located at or near the aortic trifurcation were included. Four of 7 dogs were non‐ambulatory. Hind limbs were paretic in 5 dogs, paralyzed in 1 dog, and claudication alone was noted in 1 dog. Five of the 7 dogs had protein‐losing nephropathy (PLN). Of 5 dogs with PLN, 1 had protein‐losing enteropathy (PLE) and controlled hypothyroidism and 1 had caudal aortic chondrosarcoma. Two dogs had no identified underlying disease. Angiography was performed before catheter directed thrombolysis and stent placement. No deaths occurred during the procedure. Postoperative complications included pain (4/7), bruising and edema (3/7), bruising only (1/7), and edema only (1/7). Median survival time (MST) of the 7 dogs was 264 days (range, 1‐1053 days). Five of 7 dogs were ambulatory within 2 days of stenting and survived to discharge with a MST of 425 days (range, 208‐1053 days). Conclusions and Clinical Importance Stenting of the aorta and aortoiliac trifurcation can provide an apparently safe and effective treatment with rapid return to ambulation for some dogs with aortic thrombosis.

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Section: Introductionmentioning

confidence: 99%

“…Combined interventional techniques such as rheolytic thrombectomy, catheter directed thrombolysis/thrombectomy, balloon angioplasty, and vascular stenting can allow for return to function without the prolonged time and protracted recovery associated with medical therapy and surgery, respectively. 1 , 12 , 15 …”

Section: Introductionmentioning

confidence: 99%

Stenting of the caudal aorta and aortic trifurcation for the treatment of thrombosis in 7 dogs

Gavin¹,

Weisse

Berent

2022

Veterinary Internal Medicne

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Administration of Other Biological Products

Prittie¹,

Stefano²

2023

Advanced Monitoring and Procedures for Small Animal Emergency and Critical Care

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Forced motion of a cylinder within a liquid-filled elastic tube – a model of minimally invasive medical procedures

2019

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This work analyzes the viscous flow and elastic deformation created by the forced axial motion of a rigid cylinder within an elastic liquid-filled tube. The examined configuration is relevant to various minimally invasive medical procedures in which slender devices are inserted into fluid-filled biological vessels, such as percutaneous revascularization, interventional radiology, endoscopies and catheterization. By applying the lubrication approximation, thin shell elastic model, as well as scaling analysis and regular and singular asymptotic schemes, the problem is examined for small and large deformation limits (relative to the gap between the cylinder and the tube). At the limit of large deformations, forced insertion of the cylinder is shown to involve three distinct regimes and time-scales: (i) initial shear dominant regime, (ii) intermediate regime of dominant fluidic pressure and a propagating viscous-peeling front, (iii) late-time quasi-steady flow regime of the fully peeled tube. A uniform solution for all regimes is presented for a suddenly applied constant force, showing initial deceleration and then acceleration of the inserted cylinder. For the case of forced extraction of the cylinder from the tube, the negative gauge pressure reduces the gap between the cylinder and the tube, increasing viscous resistance or creating friction due to contact of the tube and cylinder. Matched asymptotic schemes are used to calculate the dynamics of the near-contact and contact limits. We find that the cylinder exits the tube in a finite time for sufficiently small or large forces. However, for an intermediate range of forces the radial contact creates a steady locking of the cylinder inside the tube.

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Thrombectomy and Thrombolysis

Cited by 3 publications

References 8 publications

Stenting of the caudal aorta and aortic trifurcation for the treatment of thrombosis in 7 dogs

Stenting of the caudal aorta and aortic trifurcation for the treatment of thrombosis in 7 dogs

Administration of Other Biological Products

Forced motion of a cylinder within a liquid-filled elastic tube – a model of minimally invasive medical procedures

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