Thrombectomy with rescue aspiration catheter and distal protection with EPI filterwire in primary angioplasty for acute myocardial infarction

Chan, Kamtim; Lee, Kangyin

doi:10.1055/s-0031-1276429

Int J Angiol

2003

DOI: 10.1055/s-0031-1276429

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Thrombectomy with rescue aspiration catheter and distal protection with EPI filterwire in primary angioplasty for acute myocardial infarction

Kamtim Chan¹,

Kangyin Lee²

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2010

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“…They include a distal tip with either a single central lumen (2,5) or a combination of central and side holes (6). Different solutions, mainly based on different distal tip shapes, have been suggested (2,7,8), but their effectiveness has not been really demonstrated. A number of clinical trials (5,6,9) and in vitro tests (10,11) are reported in the literature.…”

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Numerical Simulation of Thrombus Aspiration in Two Realistic Models of Catheter Tips

et al. 2010

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Thrombus aspiration catheters are devices used to remove a blood clot from a vessel, usually prior to angioplasty or stent implantation. However, in vitro results showed that the use of different commercial devices could produce very different thrombus removals, suggesting a primary dependence on the distal tip configuration of the catheter. A computational methodology based on realistic catheter tip modeling was developed to investigate the factors affecting the thrombus suction. Two different designs were considered, either with a single central lumen or a combination of central and side holes. First, steady-state aspiration of distilled water from a reservoir was simulated and compared with experimental tests. Subsequently, the aspiration of a totally occlusive thrombus, modeled as a high viscous fluid, was simulated solving a complex two-phase (blood and thrombus) problem. In particular, the benefit of additional openings was investigated. Good matching between the steady-state experimental and numerically simulated hydraulic behaviors allowed a validation of the numerical models. Numerical results of thrombus aspiration showed that the catheter with central and side holes had a worse performance if compared with the single central lumen catheter. Indeed, the inlets in contact with both blood and thrombus preferentially aspirate blood due to its much lower viscosity. This effect hindered the aspiration of thrombus. The amount of aspirated thrombus highly depends on the complex, two-phase fluid dynamics occurring across the catheter tips. Results suggested that location of additional holes is crucial in the catheter aspiration performance.

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confidence: 99%

Numerical Simulation of Thrombus Aspiration in Two Realistic Models of Catheter Tips

et al. 2010

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Thrombectomy with rescue aspiration catheter and distal protection with EPI filterwire in primary angioplasty for acute myocardial infarction

Cited by 1 publication

References 1 publication

Numerical Simulation of Thrombus Aspiration in Two Realistic Models of Catheter Tips

Numerical Simulation of Thrombus Aspiration in Two Realistic Models of Catheter Tips

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