Cognitive radio is a technology that allows the unlicensed users to access the licensed spectrum based on sensing information perceived by the users. Cognitive radio user generally attempts to access the unutilized band of licensed user. However, the emergence/reappearance of primary users during ongoing cognitive user's transmission creates the interference at the primary receiver and data loss at cognitive receiver. In this context, the spectrum monitoring is a vital process of the cognitive radio network during data transmission to continuously monitor the primary user's presence or absence on a licensed channel. In this manuscript, we have utilized the spectrum monitoring technique on earlier existing MAC protocol for CR network to detect the emergence/reappearance of primary users throughout the data transmission period of cognitive users. The spectrum monitoring is employed to reduce the interference at primary receiver, which is measured in terms of interference power (IP) and data loss at CU receiver. The closed form expressions of data loss and IP for the monitoring and without monitoring scenarios are provided. In addition, the probability of monitoring error's (which causes misinterpretation of channel's status by the cognitive users) impact on these performance parameters is also provided and simulated. Further, earlier MAC protocol has significant amount of bandwidth wastage in case primary user disappears or reappears during cognitive user's data transmission, which is shown mathematically and simulated as well. However, incorporation of the monitoring phenomenon even with significant amount of monitoring error has reduced bandwidth wastage, which is measured in bps. In addition, the throughput calculation of the proposed system and the effect of monitoring error on the throughput of the proposed system are also seen. As per the results, the maximum data loss and IP occurred at licensed channel's busy probability value of 0.5, which is 23.22 bps and 3.487 W, respectively, at maximum monitoring error value. However, minimum data loss and IP are achieved at licensed busy channel's probability values of zero and one. In addition, the resource wastage at licensed channel's busy probability value of 0.5 is varying from 2.322 to 23.22 bps for varying the monitoring error value from 0.1 to 1, respectively, giving highest resource wastage at maximum monitoring error value.