Thymol and eugenol microemulsion for Rhiphicephalus sanguineus sensu lato control: Formulation development, field efficacy, and safety on dogs

Monteiro, Caio Márcio de Oliveira; Ferreira, Lorena Lopes; Paula, Luiza Gabriella Ferreira de; Filho, Jaires Gomes de Oliveira; Silva, Fernanda de Oliveira; Muniz, Elen Regozino; Menezes, Karolina Martins Ferreira; Camargo, Fabricio; Nonato, Rhayssa de Oliveira; Martins, Danieli Brolo; Marreto, Ricardo Neves; Borges, Lígia Miranda Ferreira

doi:10.1016/j.vetpar.2021.109501

Cited by 20 publications

(1 citation statement)

References 41 publications

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“…In conclusion, the microemulsion effectively reduces the number of larvae and affects the reproductive parameters of engorged female brown dog ticks. Still, it is also safe for dogs and maintains physical stability over two years [72].…”

Section: Effects Of Eo On the Health Status Of Pets And Animalsmentioning

confidence: 99%

Composition, Bioactivities, Safety Concerns, and Impact of Essential Oil on Pets’ and Animals’ Health

Sisubalan,

Sivamaruthi,

Kesika

et al. 2023

Preprint

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Essential oils (EOs) are highly concentrated and volatile blends of nonpolar substances, are derived from aromatic plant components and comprise terpenes, terpenoids and phenylpropanoids, exhibiting diverse biological and pharmacological properties. The burgeoning pet industry is interested in EOs as a potential solution for common health issues in domestic animals, particularly in addressing antimicrobial resistance. The present study summarizes the composition, properties, benefits, safety considerations, and effects of EOs on pets and animals. The applications of EOs range from antimicrobial effects to antioxidant, anti-inflammatory, and anticancer activities etc. Furthermore, EOs are used extensively in various industries, including beauty care products, detergents, and fragrances. The chemical constituents of EOs, exemplified by eucalyptus EO and rosemary EO, highlight their distinct aromatic profiles and potential benefits. Nevertheless, understanding the chemical makeup of EOs is fundamental in assessing their potential impacts on biological systems. Safety considerations, including potential toxicity, are essential when incorporating EOs into animal care routines. The feed additives incorporating EOs have shown promise in influencing gut microbiota balance, reducing inflammation, and acting as antioxidants. However, cautious application is paramount, considering the potential risks associated with high doses or multiple administrations. Preliminary studies suggest low toxicity levels, but further research is required to evaluate the safety of EOs. Though studies reported the beneficial effects of EOs on pets and animals, further research is needed to validate the findings in real-world conditions. The paper also discussed the regulatory considerations and future perspectives on applying EOs in veterinary medicine.

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Section: Effects Of Eo On the Health Status Of Pets And Animalsmentioning

confidence: 99%