Thyroid control of small intestinal oxygen consumption and the influence of sodium ions, oxyhen tension, glucose and anaesthesia.

Levin, Fredrik; Syme, Gabrielle

doi:10.1113/jphysiol.1975.sp010845

Cited by 27 publications

(26 citation statements)

References 28 publications

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“…Thiouracil: 6-n-propyl-2-thiouracil (Koch-Light Ltd) was administered as an 0-5 mmol/1 solution in the drinking water (ad libitum) (Levin & Syme, 1975). Tri-iodothyronine (T3) and thyroxine (T4).-T3 or T4 (12//g in 0-1 ml arachis oil) were injected subcutaneously once daily for 6 days, blood being taken on the seventh day.…”

Section: Experimental Treatmentsmentioning

confidence: 99%

Effect of Thyroid Status on the Thyrotrophin-Releasing Hormone-Degrading Activity of Rat Serum

White¹,

Jeffcoate²,

Griffiths³

et al. 1976

Journal of Endocrinology

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The TRH-degrading activity of rat serum in vitro is five times more potent than that of human serum. In rats, it is significantly reduced in hypothyroidism (thiouracil-induced) and significantly increased in hyperthyroidism (T3 or T4-induced). This suggests a possible role in the regulation of adenohypophysial-thyroid function which is probably, in turn, dependent on thyroid hormone, rather than TSH, levels.

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Section: Experimental Treatmentsmentioning

confidence: 99%

Effect of Thyroid Status on the Thyrotrophin-Releasing Hormone-Degrading Activity of Rat Serum

White¹,

Jeffcoate²,

Griffiths³

et al. 1976

Journal of Endocrinology

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“…Overall, the data did not confirm an association between a decreased incidence of ascites resulting from maternal hyperthyroidism and intestinal morphology in progeny chicks. However, this would not completely exclude the involvement of intestine in this respect, because it has been stated that TH influences the oxygen consumption without gross alterations in the intestinal morphology (Levin and Syme 1975). What the causal mechanisms of the lower incidence of ascites in broilers produced from the HYPER hens are, remains, however, an open question.…”

Section: Itemmentioning

confidence: 99%

Growth performance and intestinal morphology in broiler chickens produced from hyperthyroid breeder hens

et al. 2013

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An association between induced maternal hyperthyroidism and a decreased incidence of cold-induced ascites in broiler chickens has been reported recently. There are also reports suggesting that thyroid hormones have an effect on intestine, a high oxygen-demanding organ. The present study aimed to determine whether the ascites-attenuating effect of maternal hyperthyroidism is associated with morphological changes in intestine and with probable adverse effects on growth performance in progeny chicks. Eighty-eight broiler breeder hens were allotted to control or hyperthyroid [HYPER; thyroxine-treated] groups, and artificially inseminated. Hatching eggs (n = 924) were incubated and day-old male chicks (n = 288) were reared for 42 days under standard or low ambient temperature. Plasma thyroxine was higher in the HYPER hens and their embryos at internal pipping. Maternal hyperthyroidism did not adversely affect the feed : gain ratio and carcass weight, whereas cold stress impaired them. A higher relative weight was found at 42 days of age for all intestinal regions at low ambient temperature. The duodenal and jejunal crypt depths (CD) were lower in HYPER group at 7 days of age. Cold exposure decreased the duodenal and jejunal villus height and CD, and increased the ileal goblet cell number at 21 days. On Day 42, higher values were recorded for CD, goblet cell number, and epithelial thickness of different intestinal regions in cold-exposed birds. In conclusion, growth performance was not adversely influenced by maternal hyperthyroidism and its minimal early effect on intestinal morphology does not appear to be the underlying mechanism for decreased incidence of ascites in broilers.

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“…It is of interest to note that the proportion of ouabain-sensitive respiration in the duodenal mucosa of non-lactating cows, fed at maintenance, was similar to that reported for adult, maintenance-fed rats (Levin and Syme 1975;Liberman et al 1979) …”

mentioning

confidence: 89%

The Effect of Lactation on Ouabain-Sensitive Respiration of the Duodenal Mucosa of Cows

McBride¹,

Milligan²

1984

Can. J. Anim. Sci.

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McBnIoE, B. W. eNo Mrlr-rcnN, L. P. 1984. The effect of lactation on ouabainsensitive respiration of the duodenal mucosa of cows. Can. J. Anim. Sci. 64: 817-824.Total Or consumption, ouabain-sensitive and ouabain-insensitive respiration rares were measured for the duodenal mucosa of non-lactating and lactating cows. Sup-port of Na*, K*-ATPase activity, as measured by ouabain-sensitive respiration, accounted for 55va of total mucosal respiration of the cows at peak lactation. In mid-lactation and during the non-lactating period the proportion of o, uptake inhibited by ouabain declined to 34-35vo; the amount of ouabain-sensitive o, uptake declined from 3.6-4.0 to 2.

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Thyroid control of small intestinal oxygen consumption and the influence of sodium ions, oxyhen tension, glucose and anaesthesia.

Cited by 27 publications

References 28 publications

Effect of Thyroid Status on the Thyrotrophin-Releasing Hormone-Degrading Activity of Rat Serum

Effect of Thyroid Status on the Thyrotrophin-Releasing Hormone-Degrading Activity of Rat Serum

Growth performance and intestinal morphology in broiler chickens produced from hyperthyroid breeder hens

The Effect of Lactation on Ouabain-Sensitive Respiration of the Duodenal Mucosa of Cows

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