2015
DOI: 10.3389/fendo.2015.00087
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Thyroid Function/Antibodies in Sudanese Patients with Preeclampsia

Abstract: Preeclampsia is an important cause of maternal and prenatal morbidity and mortality in the developing countries. Changes in thyroid function/antibodies profiles in preeclamptic women are controversial and were never investigated before in Sudan. A case–control study was conducted at Medani Hospital, Sudan, to investigate thyroid function/antibodies in preeclampsia. The sociodemographic, medical history was gathered using questionnaires. Thyroid hormones [thyroid-stimulating hormone (TSH), free tri-iodothyronin… Show more

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Cited by 16 publications
(11 citation statements)
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“…Specific anti-TPO and anti-thyroglobulin (anti-TG) antibody profiles were analyzed using commercial ELISA (Euroimmun, Lübeck, Germany) kits as we described elsewhere [13]. …”
Section: Methodsmentioning
confidence: 99%
“…Specific anti-TPO and anti-thyroglobulin (anti-TG) antibody profiles were analyzed using commercial ELISA (Euroimmun, Lübeck, Germany) kits as we described elsewhere [13]. …”
Section: Methodsmentioning
confidence: 99%
“…We have previously shown that preeclampsia is associated with oxidative stress [21]. The current study was carried to investigate the levels of serum calcium, magnesium, zinc and copper in preeclampsia, to find their potential role in the etiology/pathogenesis of preeclampsia and to add to the previous research on preeclampsia in Sudan [2123]. …”
Section: Introductionmentioning
confidence: 99%
“…A volume of 5 ml of venous blood was taken from each patient, allowed to clot, centrifuged, and stored at −20 °C until assay of thyroid hormones (TSH, FT3, FT4) using the immunoassay analyzer AIA 360 TOSOH (Japan), guided by the manufacturer’s instructions as described previously [15]. Noteworthy, the aim of present study was to get TSRRs of TSH, FT3 and FT4 regardless of parity or residence.…”
Section: Methodsmentioning
confidence: 99%
“…A total required sample size of 63 women was calculated using a formula for a longitudinal study and the difference in the mean of the proposed variables (TSH, FT3, and FT4 as in our previous study [15]) that would provide 80 % power to detect a 5 % difference at α = 0.05. We assumed that 10 % of women will be lost during follow-up or will not respond.…”
Section: Methodsmentioning
confidence: 99%
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