Thyroid hemiagenesis associated with medullary or papillary carcinoma: Report of cases

Wang, M M Jianbiao; Gao, Li; Song, Muye

doi:10.1002/hed.23501

Cited by 17 publications

(16 citation statements)

References 35 publications

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“…Searching for the association between thyroid hemiagenesis and cancer, we found 15 patients (14 females and 1 male, mean age 48.57±15.9, range 14 to 74 years) 2,4,5,8,[10][11][12][13][14][15][16][17][18][19][20] (Table 3). Thyroid hemiagenesis was on the left in 8 cases (7 F and 1 M, mean age 50.5±17.1, range 14-69) and on the right in 6 (all women; mean age 47.8±16.5, range 30-74), while only one woman presented isolated isthmus absence.…”

Section: Discussionmentioning

confidence: 99%

Thyroid hemiagenesis, Graves’ disease and differentiated thyroid cancer: a very rare association: case report and review of literature

Campennì¹,

Giovinazzo

Curtò

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Thyroid hemiagenesis, Graves’ disease and differentiated thyroid cancer: a very rare association: case report and review of literature

Campennì¹,

Giovinazzo

Curtò

et al. 2015

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“…Various pathologies reported are multinodular goitre, Grave's disease, Hashimoto's thyroiditis, papillary thyroid cancer and primary hyperparathyroidism [8,9]. Incidence of thyroid neoplasms is higher in these set of patients both as a result of higher TSH levels and due to higher incidence of nodules in them.…”

Section: Discussionmentioning

confidence: 99%

Thyroid Hemiagenesis: Role of an Oncologist

Vd¹,

Nair²,

Datta³

et al. 2015

JCR

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Abstract:Thyroid hemiagenesis is a rare congenital anomaly in which one lobe of thyroid fails to develop; which may or may not be associated with failure of development of the isthmus. Most of the patients remain asymptomatic. Thyroid pathologies are more common in these patients than the normal population. Euthyroid cases without any above mentioned disorders need reassurance for the patient. Importance of this case lies in two important things. First thyroid hemiagenesis is associated with increased incidence of other associated disorders including malignancy. Hence close follow up is essential. Secondly, when in euthyroid status, proper patient counselling and avoidance of unnecessary surgery are of paramount importance to avoid permanent hypothyroidism.

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“…It is diagnosed by imaging methods including ultrasonography, CT, MRI and/or thyroid scanning. 3,5) Treatment strategy for thyroid carcinoma patients with hemiagenesis was not different in patients with anatomically normal thyroid gland. 3,5) However, the location of parathyroid gland and the course of recurrent laryngeal nerve could differ from the normal thyroid gland, hence, greater intra-operative care is required from the surgeon.…”

Section: -48)mentioning

confidence: 97%

“…The isthmus could be found in 10 patients (Table 1). 4,5,[8][9][10][11][12][13] Hemiagenesis is usually asymptomatic, if not concomitant with another condition causing hyper-or hypothyroidism. It is diagnosed by imaging methods including ultrasonography, CT, MRI and/or thyroid scanning.…”

Section: -48)mentioning

confidence: 99%

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Thyroid Hemiagenesis Associated with Papillary Thyroid Carcinoma

et al. 2016

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Thyroid hemiagenesis is a rare congenital anomaly that is caused by a developmental defect of a thyroid. Previous reports indicate that thyroid cancer associated with hemiagenesis is extremely rare. A 47-year-old woman presented with single nodule in the right thyroid gland that was incidentally detected during a routine medical checkup. Ultrasonography showed a 1.5×1.2 cm sized ill-defined irregular hypoehoic nodule in the right thyroid and the isthmus was present. However, the left thyroid was not seen and thyroid was disconnected at left paraisthmic area. Fine-needle aspiration cytology confirmed that the right thyroid nodule was papillary thyroid carcinoma. Total thyroidectomy with bilateral central compartment node dissection was performed. Permanent pathologic finding was 1.3×1 cm sized classical type papillary thyroid carcinoma with nodular hyperplasia. There was extensive lymphatic invasion and 3 metastatic lymph nodes out of 4 in central compartment. In conclusion, although thyroid hemiagenesis associated with thyroid carcinoma is extremely rare, treatment strategy is not different with patients with normal anatomy. And the possibility of developing a thyroid carcinoma should be considered in patients with hemiagenesis. Furthermore, it requires awareness of anatomical difference around the thyroid gland during operation.

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Thyroid hemiagenesis associated with medullary or papillary carcinoma: Report of cases

Abstract: Our case represents the first reported case of association between thyroid hemiagenesis and MTC.

Cited by 17 publications

References 35 publications

Thyroid hemiagenesis, Graves’ disease and differentiated thyroid cancer: a very rare association: case report and review of literature

Thyroid hemiagenesis, Graves’ disease and differentiated thyroid cancer: a very rare association: case report and review of literature

Thyroid Hemiagenesis: Role of an Oncologist

Thyroid Hemiagenesis Associated with Papillary Thyroid Carcinoma

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