Thyroid Hormones, Iodine and Iodides, and Antithyroid Drugs

Bhave, Vishakha; Patel, Anuj; Deshmukh, Rahul; Singh, Ajay N.; Mody, Vicky

doi:10.1016/bs.seda.2018.08.011

Cited by 3 publications

(3 citation statements)

References 57 publications

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“…The radioactive iodine isotopes; ( 124 I, 125 I, and 131 I) are used in nuclear medicine 4 . 131 I isotope plays an important role in diagnose and treat various thyroid diseases, moreover it is used for diagnostic and therapeutic purposes of Neuroblastomas, Pheochromocytomas and Paragangliomas 5 , 6 . 131 I-Hippuran, 131 I-MIBG, Oral-NaI 131 and 131 I-capsules are prepared for use in the purposes of nuclear medicine 4 , 5 .…”

Section: Introductionmentioning

confidence: 99%

“…131 I isotope plays an important role in diagnose and treat various thyroid diseases, moreover it is used for diagnostic and therapeutic purposes of Neuroblastomas, Pheochromocytomas and Paragangliomas 5 , 6 . 131 I-Hippuran, 131 I-MIBG, Oral-NaI 131 and 131 I-capsules are prepared for use in the purposes of nuclear medicine 4 , 5 . It is noticed that residual traces of radioactive iodine isotopes are present in the urine of patients receiving the radioactive iodine therapy.…”

Section: Introductionmentioning

confidence: 99%

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Impact of (nano ZnO/multi-wall CNTs) prepared by arc discharge method on the removal efficiency of stable iodine 127I and radioactive iodine 131I from water

El-Khatib,

Bondouk,

Omar

et al. 2024

Sci Rep

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Radioactive iodine isotopes especially 131I are used for diagnosis and treatment of different types of cancer diseases. Due to the leak of radioactive iodine into the patient’s urine in turn, the wastewater would be contaminated, so it is worth preparing a novel adsorption green material to remove the radioactive iodine from wastewater efficiently. The removal of 127I and 131I contaminants from aqueous solution is a problem of interest. Therefore, this work presents a new study for removing the stable iodine 127I− and radioactive iodine 131I from aqueous solutions by using the novel nano adsorbent (Nano ZnO/MWCNTs) which is synthesized by the arc discharge method. It is an economic method for treating contaminated water from undesired dissolved iodine isotopes. The optimal conditions for maximum removal are (5 mg/100 ml) as optimum dose with shacking (200 rpm) for contact time of (60 min), at (25 °C) in an acidic medium of (pH = 5). After the adsorption process, the solution is filtrated and the residual iodide (127I−) is measured at a maximum UV wavelength absorbance of 225 nm. The maximum adsorption capacity is (15.25 mg/g); therefore the prepared nano adsorbent (Nano ZnO/MWCNTs) is suitable for treating polluted water from low iodide concentrations. The adsorption mechanism of 127I− on to the surface of (Nano ZnO/MWCNTs) is multilayer physical adsorption according to Freundlich isotherm model and obeys the Pseudo-first order kinetic model. According to Temkin isotherm model the adsorption is exothermic. The removal efficiency of Nano ZnO/MWCNTs for stable iodine (127I−) from aqueous solutions has reached 97.23%, 89.75%, and 64.78% in case of initial concentrations; 0.1843 ppm, 0.5014 ppm and 1.0331 ppm, respectively. For the prepared radio iodine (131I−) solution of radioactivity (20 µCi), the dose of nano adsorbent was (10 mg/100 ml) and the contact time was (60 min) at (pH = 5) with shacking (200 rpm) at (25 °C). The filtration process was done by using a syringe filter of a pore size (450 nm) after 2 days to equilibrate. The removal efficiency reached (34.16%) after the first cycle of treatment and the percentage of residual radio iodine was (65.86%). The removal efficiency reached (94.76%) after five cycles of treatment and the percentage of residual radio iodine was (5.24%). This last percentage was less than (42.15%) which produces due to the natural decay during 10 days.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impact of (nano ZnO/multi-wall CNTs) prepared by arc discharge method on the removal efficiency of stable iodine 127I and radioactive iodine 131I from water

El-Khatib,

Bondouk,

Omar

et al. 2024

Sci Rep

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“…This is in comparison to external radiation treatment which can take several weeks. 125 I brachytherapy has been used to treat brain tumours since 1979 72 . Brain tumours that are less than 5–6 cm and are well defined can be treated with brachytherapy 73 ; brain tumour types that have been treated with brachytherapy include anaplastic astrocytomas, glioblastomas, meningiomas, metastases and low‐grade gliomas 74 …”

Section: Introductionmentioning

confidence: 99%

Use of radioiodine in nuclear medicine—A brief overview

Ferris

Carroll

Jenner³

et al. 2020

Labelled Comp Radiopharmac

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Radioiodines have a long history in nuclear medicine. Herein, we discuss the production, properties and applications of these versatile iodine‐based imaging and theragnostic agents. There are 38 isotopes of iodine (I) including one stable form (127I). The most common radionuclides used in medical imaging and treatment, including Iodine‐123 (123I), Iodine‐124 (124I), Iodine‐125 (125I) and Iodine‐131 (131I), are discussed in this review.

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