1963
DOI: 10.1210/endo-73-2-244
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Thyroid Hypocalcemic Principle and Recurrent Laryngeal Nerve Injury as Factors Affecting the Response to Parathyroidectomy in Rats1

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Cited by 357 publications
(77 citation statements)
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“…Calcitonin (CT), the hypocalcemic hypophosphatemic hormone [1,2], is the specific marker for medullary carcinoma of the thyroid (MCT) [3] a tumor existing either in sporadic or familial (autosomal dominant) form. The hormone is also produced ectopically by a large number of tumors thought to arise from cells sharing either common histochemical characteristics, the Apud concept [4], or the same embryological origin, the neural crest [5].…”
Section: Introductionmentioning
confidence: 99%
“…Calcitonin (CT), the hypocalcemic hypophosphatemic hormone [1,2], is the specific marker for medullary carcinoma of the thyroid (MCT) [3] a tumor existing either in sporadic or familial (autosomal dominant) form. The hormone is also produced ectopically by a large number of tumors thought to arise from cells sharing either common histochemical characteristics, the Apud concept [4], or the same embryological origin, the neural crest [5].…”
Section: Introductionmentioning
confidence: 99%
“…Calcitonin, the hypocalcemic hypophosphatemic hormone (Copp et al, 1962;Hirsch et al, 1963), is involved in the regulation of calcium metabolism. The hormone is secreted by the C cells, localized in the thyroid in mammalia and in the ultimobranchial glands in lower vertebrates.…”
Section: Introductionmentioning
confidence: 99%
“…Hirsch, Gauthier, and Munson (1963) made a second and highly significant observation. These investigators noted that parathyroidectomy by the Erdheim cautery technique, which involves hot wire cauterization of adjacent thyroid tissue in the rat, resulted in a much more rapid and profound hypocalcemia than simple surgical Parathyroidectomy.…”
mentioning
confidence: 89%