Thyroid nodule size and the risk of malignancy

Puca, Entela; Lumi, Ema; Olldashi, Blertina; Bitri, Sonila; Ylli, Dorina; Ylli, Agron; Puca, Edmond

doi:10.1530/endoabs.49.ep1470

Cited by 2 publications

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“…Based on her clinical course, laboratory findings and staying at home, we concluded that her severe hypocalcaemia was mainly related to COVID-19 infection and especially caused by endotoxemia. The deficiency of vitamin D in Albania is a common finding ( 7 ). The aetiology of hypocalcaemia in critical illness is multifactorial starting with food, non-exposure to sunlight and severe infectious diseases.…”

Section: Discussionmentioning

confidence: 99%

Severe hypocalcaemia in a COVID-19 female patient

Puca

Puca²,

Pipero

et al. 2021

Endocrinology, Diabetes &Amp; Metabolism Case Reports

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Summary Comorbidities are a risk factor for patients with COVID-19 and the mechanisms of disease remain unclear. The aim of this paper is to present a case report of an COVID-19 patient with severe hypocalcaemia. This is a report of an 81-year-old female, suffered from myalgia and fatigue for more than 3–4 weeks. Fever and cough appear 2 days before she presented to the emergency room. On physical examination, she was febrile with a temperature of 38.8°C, accompanied by cough, sore throat, headache, fatigue, and muscle ache. Her past medical history was remarkable with no chronic disease. She had lymphopenia. Laboratory test revealed moderate liver dysfunction, hypoalbuminemia, and severe hypocalcaemia (serum corrected calcium level: 5.7 mg/dL). Parathyroid hormone (PTH) was 107.9 pg/mL (range: 15–65) and 25(OH)2D levels was 4.5 ng/mL (range: 25–80). Chest CT scan detected peripheral ground-glass opacity. Throat swab for coronavirus by RT-PCR assay tested positive for the virus. She was treated with lopinavir/ritonavir, third generation cephalosporin, anticoagulant, daily high-dose calcium acetate, vitamin D3, fresh frozen plasma and oxygen therapy. She was discharged after two negative throat swab tests for coronavirus by conventional RT-PCR. Learning points Comorbidities are a risk factor for patients with COVID-19. Laboratory findings are unspecific in COVID-19 patients; laboratory abnormalities include lymphopenia, elevated of LDH, CPK and the inflammatory markers, such as C reactive protein, ferritinemia and the erythrocyte sedimentation rate. In addition to inflammatory markers, in COVID-19 patients it is crucial to check the level of vitamin D and calcium. There may be a correlation between vitamin D deficiency and the severity of COVID-19 disease.

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Section: Discussionmentioning

confidence: 99%

Severe hypocalcaemia in a COVID-19 female patient

Puca

Puca²,

Pipero

et al. 2021

Endocrinology, Diabetes &Amp; Metabolism Case Reports

Self Cite

View full text Add to dashboard Cite

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A Clinical Study of Solitary Thyroid Nodule

Shiva¹,

Ramachandra

2021

IJAR

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A solitary thyroid nodule (STN) is dened as a palpable discreet swelling in an other wise normal thyroid gland. Found to affect 4-7% of total population with female to male ratio being 4:1. majority of STN are benign. Benign causes include colloid goiter. and dominant nodule of multi nodular goiter. Incidence of malignancies is around 5- 10%. A systemic approach is needed to evaluate and treat STN.

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Thyroid nodule size and the risk of malignancy

Cited by 2 publications

References 0 publications

Severe hypocalcaemia in a COVID-19 female patient

Severe hypocalcaemia in a COVID-19 female patient

A Clinical Study of Solitary Thyroid Nodule

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