Thyrotropin Level and Thyroid Volume for Prediction of Hypothyroidism Following Hemithyroidectomy in an Asian Patient Cohort

Moon, Hyeong‐Gon; Jung, Eun Jung; Park, Soon Tae; Jung, Tae Sik; Jeong, Chi Young; Ju, Young Tae; Lee, Young Joon; Hong, Soon Chan; Choi, Sang Kyung; Ha, Woo Song

doi:10.1007/s00268-008-9717-3

Cited by 41 publications

(44 citation statements)

References 29 publications

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“…Patients who developed post-hemithyroidectomy hypothyroidism were found to have a significant smaller body surface area (BSA)-adjusted remnant thyroid volume than patients who remained euthyroid (Moon et al, 2008). Another predictive factor may be BSA-adjusted remnant thyroid volume, determined by calculating remnant thyroid volume/BSA ratio.…”

Section: Amount Of Remnant Thyroid Glandmentioning

confidence: 99%

“…An alternative risk-scoring system using two factors, TSH concentration and remnant thyroid volume, was based on the results of logistic regression analyses (Moon et al, 2008). This score system was developed using independently predictive factors, with the highest score of each variable determined by its β regression coefficient.…”

Section: Johner Et Al (2011) 117mentioning

confidence: 99%

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Hypothyroidism After Hemithyroidectomy: Incidence, Risk Factors, Natural History and Management

Lee¹,

Chung²

2012

Hypothyroidism - Influences and Treatments

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Section: Amount Of Remnant Thyroid Glandmentioning

confidence: 99%

Section: Johner Et Al (2011) 117mentioning

confidence: 99%

Hypothyroidism After Hemithyroidectomy: Incidence, Risk Factors, Natural History and Management

Lee¹,

Chung²

2012

Hypothyroidism - Influences and Treatments

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“…Because only one lobe of the thyroid gland is removed, hemithyroidectomy is associated with a lower incidence of postoperative hypocalcemia and recurrent and superior laryngeal nerve injury than in total thyroidectomy. However, hypothyroidism may develop in 7.4 -36.6% cases after thyroid hemithyroidectomy [6,9,10]. It is very important not only to select the patients at risk of developing the hypothyroidism but also to help a patient and a doctor make a decision choosing a type of operation: hemithyroidectomy or thyroidectomy, if there are minimal alterations of structure (less than 1 cm in diameter) in the remaining gland.…”

Section: Discussionmentioning

confidence: 99%

“…The reported incidence of hypothyroidism after hemithyroidectomy ranges from 7.4 to 36.6% [6,9,10]. An early diagnosis of the subclinical state, followed by myxoedema, is very important.…”

Section: Introductionmentioning

confidence: 99%

“…In more recent years, physicians stopped administering thyroid suppression therapy during the immediate postoperative period [6]. The emergence of the new trend was based on two developments: the publication of data that put into question the efficacy of levothyroxine therapy and heightened awareness of the morbidity associated with levothyroxine [7,8].…”

Section: Introductionmentioning

confidence: 99%

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Prognosis of thyroid function after hemithyroidectomy

et al. 2011

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AbstractIdentify criteria and create a risk scoring system to predict hypothyroidism after hemithyroidectomy. We have retrospectively studied 216 cases of patients with goiter who had undergone hemithyroidectomy from January 2002 to December 2007 at Vilnius University Hospital Santariškių Klinikos. Patients were divided into two groups according to their thyroid function after hemithyroidectomy: 168 (77.8%) patients’ thyroid function was normal (group A), 48 (22.2%) patients had symptoms of hypothyroidism (group B). The relationship between groups and parameters such as patients’ sex, age, patient’s weight, preoperative serum thyroid-stimulating hormone (TSH) level, weight of the remnant gland, ratio of the remaining thyroid gland weight to patient’s weight was statistically analysed. The patients’ mean age was 41.6 ± 14.1 years in group A and 52.9 ± 13.9 years in group B (p=0.0002). The mean preoperative TSH level was 0.79 ± 0.5 mU/L in group A, compared with 1.42 ± 1.00 mU/L in group B (p= 0.005). The mean ratio of the remaining thyroid gland weight to patient’s weight was 0.102 ± 0.053 g/kg in group A and 0.063 ± 0.027 g/kg in group B (p=0.04). The groups did not establish a significant difference between patients’ sex, patient’s weight or weight of the remaining gland. Patient’s age, preoperative serum TSH level, ratio of the remaining thyroid gland weight to patient’s weight is the main factors of hypothyroidism after hemithyroidectomy. A risk scoring system was created to predict hypothyroidism after hemithyroidectomy before the operation.

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Predictors of thyroxine replacement following hemithyroidectomy in a south east Asian cohort

Tan

et al. 2018

Head & Neck

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Background Thyroxine replacement following a hemithyroidectomy is not commonly discussed during consent for the procedure as the risk of hypothyroidism is perceived to be low. Methods Retrospective review of 901 patients who underwent hemithyroidectomy at a tertiary referral institution during the period January 2000 to December 2015. The main outcome studied was the overall incidence of hypothyroidism and the associated risk factors. Results Hypothyroidism developed in 123 (13%) patients and 94 patients (10%) required hormone supplementation over a mean follow up of 21 months (range 1‐168 months). Preoperative TSH of more than 2.5 was seen in 38 of 123 (31%) of patients. Presence of diffuse thyroiditis was the only independent risk factor on multivariate analysis (P = 0.002) found to be associated with the development of hypothyroidism. Conclusion After thyroid lobectomy, approximately one in 10 patients requiring thyroid hormone treatment for hypothyroidism. Presence of diffuse thyroiditis is a significant risk factor for hypothyroidism.

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Thyrotropin Level and Thyroid Volume for Prediction of Hypothyroidism Following Hemithyroidectomy in an Asian Patient Cohort

Cited by 41 publications

References 29 publications

Hypothyroidism After Hemithyroidectomy: Incidence, Risk Factors, Natural History and Management

Hypothyroidism After Hemithyroidectomy: Incidence, Risk Factors, Natural History and Management

Prognosis of thyroid function after hemithyroidectomy

Predictors of thyroxine replacement following hemithyroidectomy in a south east Asian cohort

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