Time course and predictors for neoaortic root dilatation and neoaortic valve regurgitation during adult life after arterial switch operation

Soriano, Joaquín Rueda; Puras, María José Rodríguez; Fuentes, Francisco Buendía; Rodríguez, Amadeo Wals; Sáez, Ana Osa; Pulido, Ildefonso; Ramón-Llin, Jaime Agüero; García, Begoña Manso; Albert, Beatriz Insa; Navarro, Silvia; Martínez‐Dolz, Luis; Gallego, Pastora

doi:10.1016/j.rec.2020.01.022

Cited by 1 publication

(3 citation statements)

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“…As expected as a consequence of the ASO, 29,30 the aortic root diameter was larger in patients with D-TGA (p < .001) who also showed a higher peak pulmonary artery peak gradient (p < .001) than controls.…”

Section: Left Ventricle Function Volume and Masssupporting

confidence: 72%

“…It is known that these patients have poor tolerance of adverse hemodynamic situations as, for example, severe aortic regurgitation. In this sense, the vast majority of D‐TGA patients after ASO who developed severe aortic regurgitation during childhood or young adulthood underwent surgery for clinical symptoms or left ventricular dysfunction 29 . The aim of this study is purely descriptive.…”

Section: Discussionmentioning

confidence: 99%

“…In this sense, the vast majority of D-TGA patients after ASO who developed severe aortic regurgitation during childhood or young adulthood underwent surgery for clinical symptoms or left ventricular dysfunction. 29 The aim of this study is purely descriptive. Long-term longitudinal follow-up studies are needed to confirm if abnormal LV and LA strain might add prognostic value in patients with D-TGA after ASO.…”

Section: Discussionmentioning

confidence: 99%

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Left atrial strain in adults after the arterial switch operation for transposition of the great arteries

Buendía‐Fuentes,

Lozano‐Edo,

Jover‐Pastor

et al. 2024

Echocardiography

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BackgroundNo study has focused on left atrial (LA) function assessed by echocardiography in adult patients with simple D‐TGA after arterial switch operation (ASO). We aimed to describe LA strain parameters in these patients.MethodsA prospective cohort study including 42 adult patients with simple D‐TGA after ASO and 33 aged‐matched controls. Phasic LA and LV global longitudinal strain (GLS) were obtained by transthoracic 2D‐speckle tracking echocardiography (STE). Volumetric and functional analysis of LA and LV were also evaluated by 2D and 3D analysis. A multivariable model was performed to investigate the variables that best differentiate patients with D‐TGA from healthy controls.ResultsLA strain parameters in D‐TGA patients were within the normal range described for healthy subjects. However, the three LA strain parameters (Reservoir, Conduit, and Contraction) were lower in patients (LASr: 31.13 ± 7.67 vs. 49.71 ± 8.38; LAS cd: ‐22.91 ± 5.69 vs. ‐34.55 ± 6.54; LASct: ‐8.14 ± 4.93 vs. ‐15.15 ± 6.07, p < .001 for all three comparisons). LA volumes were similar between patients and controls.LV‐GLS remained significantly lower in the D‐TGA group than in controls (‐17.29 ± 2.68 vs. ‐21.98 ± 1.84, p < .001).D‐TGA patients had evidence of worse LV ejection fraction measured by the Teichholz method (63.38 ± 8.23 vs. 69.28 ± 5.92, p = .001) and 3D analysis (57.97% ± 4.16 vs. 60.67 ± 3.39, p = .011) and diastolic dysfunction as compared to healthy controls.LV‐GLS and conduit LAS were the variables best differentiating patients with D‐TGA from healthy controls.ConclusionsLA strain is impaired in young adults with simple D‐TGA late after the ASO, probably in agreement with some degree of LV dysfunction previously described.

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Section: Left Ventricle Function Volume and Masssupporting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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