Time-course of changes in indirect markers of muscle damage responses following a 130-km cycling race

Abstract

DOI: http://dx.doi.org/10.5007/1980-0037.2016v18n3p322 The purpose of the present investigation was to identify the effects of a 130-km cycling race on indices of biochemical indirect markers of muscle damage and muscle soreness responses during a 72-hour recovery period. Fifteen endurance-trained male cyclists which were competing for more than 2 years and were involved in systematic training at least of 3 days/wk underwent a collection of indirect biochemical markers of muscle damage (CK, LDH, Myo) and delayed onset of muscle soreness (DOMS), at five different moments of data collection: before (PRE) and immediately after (POST) a 130-km cycling race, and 24, 48, 72 hours following the cycling race. CK and LDH plasma concentrations significantly increased POST-race (p < 0.001) and remained high throughout the 72 hour recover period (CK: p < 0.05; LDH: p < 0.001). Myo increased significantly POST-race (p < 0.001) and returned to the PRE-race values 24 hours thereafter (p < 0.05). DOMS increased significantly POST-race (p < 0.001) and returned to the PRE-race values at 48 hours after (p > 0.05). A 130-km cycling race has a noteworty effect on indices of biochemical indirect markers of muscle damage and muscle soreness responses, indicating that 72 hour recovery period do not seems to be enough for long-distance cyclist, and reinforce the propositions of scientific literature about the need of a sufficient recovery period for cycling endurance athletes.

Exercise-Induced Muscle Damage and Cardiac Stress During a Marathon Could be Associated with Dietary Intake During the Week Before the Race

“…For instance, serum MYO concentration increases immediately after exercise and peak values are normally obtained within 24 h after exercise [55]. In contrast, the increase of CK is slower with peak values usually reached between 24 h and 96 h after exercise [56]. In addition, the pre-to post-race change is usually higher in MYO than in CK, suggesting that MYO might be considered a more specific biomarker of muscle damage when measured after endurance running events [49].…”

Effects of eccentric exercise-induced delayed onset muscle soreness on endoplasmic reticulum stress-related markers

“…In the present study, it is observed to reach its maximum level at the 72nd hour. Similarly, LDH plasma levels following a 130°km cycling race increases and may remain elevated for up to 72 h in trained cyclists [36]. Peak torque deficits are most pronounced 24-48 h following DOMS-inducing exercise.…”

Creatine Supplementation Effect on Recovery Following Exercise-Induced Muscle Damage: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

“…The present meta analysis evaluated indirect muscle damage indices, including CK and LDH among trained and untrained both sexes individuals, looking at reported articles. Proteins like CK and LDH have been extensively applied as markers of muscle micro-damages (45) and usually has been evaluated to be an indirect biomarkers of post exercise muscle damage due to their easiness of identification and the relatively low cost of tests to quantify it (46,47). In spite of CK and LDH rising post exercise being much variable and affected by exercise variable and individual factors, the assessment of CK and LDH pre-and post-exercise may provide a diagnostic tool for the detection of post-exercise muscle damage, with much less invasiveness than needed in a muscle biopsy (48).…”