Time Course of Right Ventricular Remodeling after Percutaneous Atrial Septal Defect Closure: Assessment of Regional Deformation Properties with Two‐Dimensional Strain and Strain Rate Imaging

Abstract

Chronic volume overload in ASD patients causes alterations in RV deformation. Percutaneous closure results in rapid remodeling and normalization of RV deformation. The major geometrical and deformational changes are completed in 24 hours. Lateral wall S seems to reflect the RV deformational changes due to volume loading and unloading better than SR in ASD patients.

Right ventricular speckle tracking assessment for differentiation of pressure‐ versus volume‐overloaded right ventricle

“…RVFAC was lower in the pressure‐ versus the volume‐overloaded RV. Previous studies have showed that patients with PAH had a RVFAC that was impaired compared to controls (Brown et al ., ) and patients with a volume‐overloaded RV had a higher RVFAC compared to controls (Eroglu et al ., ). As RV myofiber architecture tolerates volume better than pressure overload (Greyson, ; Hsiao et al ., ), our results are in alignment with these studies.…”

“…In one study, it was shown that patients with a significant ASD had higher RVGLS strain than controls (−23·4 ± 4·5% versus −21·6 ± 4·9%) before closure of the defect (Jategaonkar et al ., ). However, another study showed only regional higher RV lateral strain values (basal and mid) before closure compared to controls (Eroglu et al ., ). In both studies, RV strain decreased following percutaneous closure.…”

Early and six-month assessment of bi-ventricular functions following surgical closure of atrial septal defect

“…Strain and strain rate assessment by two or three dimensional speckle-tracking echocardiography could have provide subtle changes in right and left ventricular functions, however this method was not used in present study. 27,28 In conclusion, we found an improvement in RV systolic function, and unchanged diastolic functions of both RV and LV following surgical closure of ASD. Left ventricular systolic function was unaffected by surgery.…”

Relation of Epicardial Fat Thickness to Subclinical Right Ventricular Dysfunction Assessed by Strain and Strain Rate Imaging in Subjects with Metabolic Syndrome: A Two‐Dimensional Speckle Tracking Echocardiography Study

“…As we excluded cases that might lead to volume and/or pressure overload in which RV contraction may become more complex, we think that evaluating only the longitudinal strain and strain rate was not an important limitation in our study. Fifth, RV strain assessed by 2DSTE software which has been mainly developed for LV strain, but studies demonstrated that the feasibility and reproducibility of RV strain were acceptable . Due to the ethical issues, we could not measure pulmonary vascular resistance with invasive methods.…”