Time-resolved fluoroimmunoassay for quantitative determination of ampicillin in cow milk samples with different fat contents

2,2′‐Bipyrimidine as Efficient Sensitizer of the Solid‐State Luminescence of Lanthanide and Uranyl Ions from Visible to Near‐Infrared

“…These properties allow time-resolved experiments to be used as very powerful analysis tools in bioinorganic chemical applications such as fluoroimmunoassays and protein labeling. [3][4][5][6][7][8][9][10] The long excited-state lifetimes and the high chromaticity of lanthanides are also interesting for applications in solid-state materials technologies. For instance, Tb 3 + , Eu 3 + , and Tm 3 + are used as green, red, and blue emitters in, respectively, trichromatic fluorescent tubes, multicolor displays, [11,12] and organic light-emitting diodes (OLEDs).…”

Assays for therapeutic drug monitoring of β-lactam antibiotics: A structured review

“…Forty-two methods were found determining one or two ␤-lactam antibiotics, 12 of which determined at least one ␤-lactam antibiotic in other body fluids such as cerebrospinal fluid (CSF), ultrafiltrate or used an alternative sampling strategy such as dried blood spots [39][40][41][42][43][44][45][46][47][48][49][50]. Twelve papers reporting immunoassays were also found [51][52][53][54][55][56][57][58][59][60][61][62].…”

“…Currently, no immunoassays are available for quantification of ␤-lactam antibiotics in human plasma. However, there are multiple assays available for trace analysis of antibiotics in milk and other food sources, with very fast analysis times [51][52][53][54][55][56][57][58][59][60][61][62]. Most of these immunoassays only give qualitative results, but some also give quantitative results, however in a concentration range that is far too low for TDM purposes as these tests are designed to quantify in the g/L range (which is necessary to detect antibiotic residues in these dietary products) whilst therapeutic values for these antibiotics in human plasma are 100-1000 times higher.…”

Detection of the circulating antigen 14-3-3 protein of Schistosoma japonicum by time-resolved fluoroimmunoassay in rabbits

“…Lanthanide chelate shows narrow and strong emission bands around 600 nm and an exceptionally long decay time, which allows the elimination of the high background of the fluorescent labels and increases the sensitivity and specificity of detection methods [20]. The sensitivity is further increased due to the dissociation-enhancement principle [21].…”