At present, most of the research studies on the seismic performance of the durability degraded reinforced concrete structure only consider the influence of a single factor. This paper comprehensively considers the factors such as concrete carbonization, steel corrosion, and bond slip performance degradation caused by other durability factors and durability damage repair and studies the influence of the above factors on the seismic performance of bridge structures. Based on the finite element model considering the bond slip and the material parameters of time-varying durability damage, the seismic performance analysis model of the pier is established considering material durability damage repair in different service periods. Then, the effect of material durability damage repair on the seismic performance of the pier is examined. The results show that the displacement of the pier top increases, the curvature of the pier bottom decreases, and the moment-curvature curve pinching phenomenon is further evident when considering the bond slip. When considering the durability damage repair of materials, the curvature considerably decreases (the maximum value is approximately 16.04%) with the extension of the service time of the bridge, and the pier damage is substantially reduced.