“…Several theories have been proposed to explain hypopigmentation, including the filtering of UV light by the growth of the organism in the skin (14), a block in the transfer of melanosomes to keratinocytes (14,89,121,153,208), and the inhibition of melanin production by azelaic acid (180,302) or by lipoxygenase (304). Other groups have suggested that the hyperpigmentation of lesions was due to inflammation (116,153), increased skin thickness, or larger numbers of organisms in the skin (153).…”