Tissue-dissolution capacity and dentin-disinfecting potential of calcium hydroxide mixed with irrigating solutions

Zehnder, Matthias; Grawehr, M.; Hasselgren, Gunnar; Waltimo, Tuomas

doi:10.1016/s1079-2104(03)00157-4

Cited by 57 publications

(61 citation statements)

References 23 publications

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“…Therefore, chemomechanical preparation and intracanal medications are used to disinfect the root canal system 2) . CH is widely used as intracanal medication due to its organic tissue dissolution potential 26) , antibacterial activity 27) , and antiinflammatory capacity 28) . Since CH is ineffective in elimination of some microorganisms such as E. faecalis, to improve its antibacterial activity, it has been combined with other materials [29][30][31][32][33][34][35][36][37][38] .…”

Section: Discussionmentioning

confidence: 99%

Antibacterial effect of triantibiotic mixture versus calcium hydroxide in combination with active agents against Enterococcus faecalis biofilm

et al. 2014

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The aim of the present study was to compare the antibacterial effect of calcium hydroxide (CH), triantibiotic mixture (TAM), and CH in combination with chlorhexidine (CHX), sodium hypochlorite (NaOCl) or colchicine (COL) against Enterococcus faecalis (E. faecalis) in surface and deep dentinal tubules. Seventy five fresh single-rooted human teeth were infected and divided into five experimental groups (n=15). The experimental groups were treated with CH+distilled water, CH+CHX, CH+NaOCl, CH+COL+distilled water and TAM+distilled water. Dentin chips obtained from surface and deep dentin of these root canals were prepared and analyzed by counting the number of colony forming units. There was significant difference between groups in the surface dentin (p<0.05). TAM showed higher antibacterial activity compared to CH-containing groups. There was no significant difference between TAM and CH-containing groups in the deep dentin (p>0.05). CH-containing medications and TAM can be used as effective disinfectants in treatment of infected root canals.

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Section: Discussionmentioning

confidence: 99%

Antibacterial effect of triantibiotic mixture versus calcium hydroxide in combination with active agents against Enterococcus faecalis biofilm

et al. 2014

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“…To render the root canal system optimally bacteria-free, intracanal medicaments have been highly advocated for root canal disinfection [15][16][17] . Calcium hydroxide (Ca(OH)2) is not an effective intracanal medicament against all types of bacterial species found in endodontic infections 4) . For example, Ca(OH)2 could not efficiently eliminate enterococci, which were isolated in one third of the patients in whom endodontic treatment had failed.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the use of intracanal medicaments has been advocated to further reduce the number of microorganisms 1) . Calcium hydroxide (Ca(OH)2) is a widely used intracanal medicament because of its antimicrobial activity 4) , organic tissue dissolution capability 4) , and anti-inflammatory effects 5) . However, clinical studies have shown that it is not possible to sterilize root canals in necrotic teeth, even with calcium hydroxide 6,7) .…”

Section: Introductionmentioning

confidence: 99%

Effects of calcium hydroxide and propolis intracanal medicaments on bond strength of resin-based endodontic sealer as assessed by push-out test

2013

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The aim of this study was to investigate the effects of calcium hydroxide (Ca(OH) 2 ) and propolis intracanal medicaments on bond strength of AH Plus to root dentin. After chemomechanical instrumentation using Revo-S rotary system, three groups of root canal specimens were prepared: 10 root canals were left untreated as controls (G1), 10 received Ca(OH) 2 intracanal medicament (G2), and another 10 received propolis intracanal medicament (G3). Canals were obturated with AH Plus and gutta-percha. After bond strength evaluation using micro push-out test, data were analyzed using ANOVA and Tamhane's test (p=0.05). At coronal and middle thirds, there were no significant differences in bond strength among the three groups (p>0.05). At apical third, G3 was significantly superior to G2 (p<0.05) and G1 (p<0.05), but there was no significant difference between G2 and G1 (p>0.05). Therefore, when AH Plus was used as the sealer in endodontic treatments, its combined use with propolis as an intracanal medicament seemed to result in favorable sealer-dentin interfacial bond strength.

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“…38 Ancak dentinin tamponlama etkisi düşünüldüğünde, 49 dentinin tamponlama etkisi düşünüldüğünde, hidroksil iyonu KH'den ayrıştıkça pH düşecek, CHX yeniden protonlanacak ve dentin tübüllerinde bakterisidal etkisini yeniden kazanacaktır. 39 NaOCl güçlü antimikrobiyal 40 ve organik doku çözücü özellikleri ile en yaygın kullanılan endodontik irrigasyon solüsyonudur.…”

Section: Discussionunclassified

Çeşitli Antiseptik Taşıyıcılarla Karıştırılan Kalsiyum Hidroksitin Enterococcus faecalis üzerindeki Antimikrobiyal Etkinliği

Akbulut

Güneşer

Eldeniz

2017

Selcuk Dental Journal

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Gereç ve Yöntemler:Altmış adet çekilmiş insan dişi örnekleri hazırlandı. Elli-beş tane kök segmenti E. faecalis ile 2 hafta boyunca enfekte edildi. Örnekler 5 deney grubuna ayrıldı (n=10) ve şu KH -antiseptik taşıyıcı karışımları uygulandı: Grup 1, KH + gliserin -distile su (7:1); Grup 2, KH + Octenisept; Grup 3, KH + %2'lik klorheksidin glukonat (CHX); Grup 4, KH + Savlex; Grup 5, KH + %5.25'lik sodyum hipoklorit (NaOCl). Antiseptik-KH karışımları 7 gün boyunca kök kanallarında bekletildi. Beş örnek sterilliği kontrol etmek için (negatif kontrol), beş örnek de pozitif kontrol olarak kullanıldı. Gates glidden frezler (# 3, 4, 5) yardımıyla kanal duvarlarından elde edilen dentin örnekleri fosfat-tamponlu salin (PBS) ve cam boncuk içeren şişelere aktarıldı ve 30 sn vortekslendi. Bakteri içeren PBS'ye seri dilüsyon yapıldı. Her bir dilüsyondan 25 μL halinde damlalar tripton soya agar plakları üzerine ekildi ve 37°C'de 48 saat inkübe edildi. Görünür koloni sayıları incelendi ve log 10 değerlerine dönüştürüldü. İstatistiksel analiz için Kruskal-Wallis ve Mann Whitney-U testleri kullanıldı. Bulgular:Negatif kontrol grubunda bakteri üremesi görülmezken pozitif kontrol grubunun bütün örneklerinde bakteri üremesi gözlemlenmiştir (log 10 3,47 CFU ml -1 ). Deney grupları arasında istatistiksel olarak anlamlı bir fark bulunmamıştır (p>0.05). KH + CHX ve KH + Savlex gruplarında E. faecalis biyofilmi tamamen elimine edilmiştir.Sonuç: Savlex, Octenisept ve NaOCl gibi çeşitli antiseptik ajanlar KH ile karıştırılarak kullanıldığında kök kanallarından E. faecalis'i elimine etmede etkili bulunmuştur. ANAHTAR KELİMELERAntimikrobiyal, E. faecalis, kanal-içi medikament, kök dentini ABSTRACT Antimicrobial activity of calcium hydroxide mixed with various antiseptic vehicles on Enterococcus faecalisBackground: The aim of this in vitro study was to test disinfection ability of different new antiseptic vehicle-calcium hydroxide (CH) combinations in root canals infected with Enterococcus faecalis using a dentin block model.

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Tissue-dissolution capacity and dentin-disinfecting potential of calcium hydroxide mixed with irrigating solutions

Cited by 57 publications

References 23 publications

Antibacterial effect of triantibiotic mixture versus calcium hydroxide in combination with active agents against Enterococcus faecalis biofilm

Antibacterial effect of triantibiotic mixture versus calcium hydroxide in combination with active agents against Enterococcus faecalis biofilm

Effects of calcium hydroxide and propolis intracanal medicaments on bond strength of resin-based endodontic sealer as assessed by push-out test

Çeşitli Antiseptik Taşıyıcılarla Karıştırılan Kalsiyum Hidroksitin Enterococcus faecalis üzerindeki Antimikrobiyal Etkinliği

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