Tissue-equivalent gel for non-invasive spatial radiation dose measurements

Bero, M.A.; Gilboy, W.B.; Glover, Paul; El-Masri, H.

doi:10.1016/s0168-583x(99)00873-3

Cited by 68 publications

(42 citation statements)

References 7 publications

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“…The FXG samples manufactured through the mixture of the concentrations of: 4% gelatin (300 Bloom-Aldrich), 0.1 mM xylenol orange, 25 mM sulphuric acid, 0.5 mM ferrous ammonium sulphate and 96% Milli Q water [10,11,19,20], were inserted in PMMA special cuvettes (30 × 30 × 1 cm 3 ). An acrylic phantom, composed of a build-up plate of 30 × 30 × 1.5 cm 3 and four plates of 30 × 30 × 2 cm 3 was used in order to provide full backscatter condition to the measurements.…”

Section: Methodsmentioning

confidence: 99%

“…The FXG has some interesting features such as, broad linear dependence with the absorbed dose from 0.5 up to 30 Gy for γ and x-ray photons [10][11][12][13], atomic effective number of 7.75 and density of 1.050 kg/m 3 , respectively near to 7.64 and 1.040 kg/m 3 for soft tissue [14]. This dosimeter is based in the Fe 2+ to Fe 3+ oxidation, forming a Fe 3+ -Xylenol complex, whose absorbance peak is centered in 585 nm.…”

Section: Introductionmentioning

confidence: 99%

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6 MV wedge photon beam profiles with the fricke xylenol gel dosimeter

Oliveira¹,

Calcina²,

Cavalcante³

et al. 2009

Braz. J. Phys.

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Wedged beam are often used in clinical radiotherapy to compensate missing tissues and dose gradients. In this work, the Fricke Xylenol Gel (FXG) dosimeter was used for 6 MV photons radiation wedge field profiles measurements, allowing to infer the wedge filter physical attenuation coefficient. This dosimeter is a chemical system of a Fe 3+ -Xylenol complex concentration, that when measured spectrophotometrically, the absorbance is directly proportional to the absorbed dose. From theses results one can infer that the FXG can be used also as an alternative dosimetric system for measurements of wedge filters.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

6 MV wedge photon beam profiles with the fricke xylenol gel dosimeter

Oliveira¹,

Calcina²,

Cavalcante³

et al. 2009

Braz. J. Phys.

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“…Ao longo do tempo, esses dosímetros sofreram modificações em suas composições, as quais podem ser feitas nas concentrações de seus reagentes a partir da solução descrita na literatura. Em 2000, Bero et al, modificou o dosímetro Fricke com a inserção do alaranjado de Xilenol e a gelatina 300 Bloom, este se tornou mais sensível para baixos valores de dose absorvida, passando-se a se chamar dosímetro Fricke Xilenol Gel (BERO et al, 2000). A aplicação do FXG vem sendo desenvolvida em diversas pesquisas envolvendo a radiação ionizante como: em equipamentos de raios-X terapêuticos (CAVINATO, Existem alguns tipos de dosímetros que são utilizados para medições da distribuição de dose da radiação, dentre eles: câmaras de ionização, filmes, termolunescentes, Fricke etc.…”

Section: Introductionunclassified

“…Este trabalho se insere nas perspectivas de Bero et al 2000, este iniciou-se as modificações dos reagentes da solução Fricke, apesar de eventualmente nunca ter sido realizado, dessa forma específica, deve-se obter géis dosimétricos adequados como esperados na literatura (BERO et al, 2001). Os objetivos específicos deste trabalho são: a) preparação da solução Fricke (FXG), b) a partir da solução FXG, fazer novas soluções com diferentes concentrações de seus reagentes; comparar as soluções modificadas com a solução FXG utilizando a técnica de espectrofotometria; c) analisar o comportamento da nova solução química através de observações, quanto a sua homogeneidade; coloração; temperatura e pH.…”

Section: Introductionunclassified

Viabilidade De Novas Formulações Do Dosímetro Químico Fricke Gel

Oliveira

Silva

2017

HOLOS

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RESUMOOs géis dosimétricos vêm sendo estudados para se tornarem mais sensíveis, a partir, das modificações em suas concentrações de seus reagentes. No dosímetro Fricke padrão (aquoso), foi adicionado o alaranjado de Xilenol e gelatina 300 Bloom para a obtenção do dosímetro Fricke Xilenol Gel (FXG). Através da interação da radiação ionizante ou com o ambiente, surgem íons que podem favorecer reações com outras moléculas e produzir radicais livres e íons secundários que podem reagir formando produtos químicos estáveis. Neste trabalho foram feitas modificações nos reagentes do FXG, com objetivo de encontrar dosímetros promissores e/ou de baixo custo, principalmente pela substituição da gelatina 300 Bloom pela gelatina comercial. Dessa maneira, foi realizada a preparação de géis dosimétricos, leituras no espectrofotômetro UV/VIS e análises das soluções. Com intuito de criar um novo dosímetro a partir da variação da concentração de seus reagentes, com maior sensibilidade. Os resultados demonstram que os géis modificados neste trabalho podem ser utilizados em pesquisa de Física Médica. PALAVRAS-CHAVE: Dosímetros, Espectrofotômetro, Fricke Xilenol Gel. VIABILITY OF NEW FORMULATIONS OF THE CHEMIST FRICKE GEL DOSIMETER ABSTRACTThe dosimeters gels have been studied to become more sensitive to changes in the starting concentrations of their reactants. In standard Fricke (aqueous) dosimeter was added the xylenol orange and 300 Bloom gelatin to obtain the Fricke dosimeter xylenol gel (FXG). Through the interaction of ionizing radiation or environmental, ions arise which can promote reactions with other molecules and produce free radicals and secondary ions that can react to form stable chemical. In this paper, modifications were made in the FXG reagents, in order to find promising and/or inexpensive dosimeters, mainly by replacement of 300 Bloom gelatine by trade gelatine. Thus, the preparation of dosimetric gels, readings in the UV/VIS spectrophotometer and analysis of the solutions were performed. Aiming to create a new dosimeter from the variation of the concentration of its reactants, with greater sensitivity. The results demonstrate that the modified gels in this work can be used in Medical Physics's research.

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“…The Fricke gel dosimeter has been studied for determine both dose and dose distribution with accuracy and precision [12,13] ) occurs when the dosimeter is exposed the ionizing radiation [14] with the oxidation yield proportional to the absorbed dose and the absorbed dose distributions can be imaged by MRI. The studied Fricke gel solutions have been prepared using 300 Bloom gelatin [8,14,19,20] that is imported and very expensive in Brazil.…”

Section: Introductionmentioning

confidence: 99%

A dosimetric evaluation of tissue equivalent phantom prepared using 270 Bloom gelatin for absorbed dose imaging in Gamma knife radiosurgery

Cavinato

Rodrigues

Cervantes

et al. 2009

J. Phys.: Conf. Ser.

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Abstract. Tissue equivalent gel phantoms have been widely studied in radiation therapy for both relative and reference dosimetry. A Fricke xylenol gel (FXG) spherical phantom was evaluated by means of magnetic resonance image method (MRI) to measure absorbed dose distribution resulted from gamma knife irradiation. The FXG phantom was prepared using 270 Bloom gelatin. The gelatin is a tissue equivalent material, of easy preparation, can be used to mold phantoms into different shapes and volumes, is commercially available and inexpensive. The results show that the Fricke gel phantom prepared with 270 Bloom gelatin satisfy the requirements to be used for the quality control in stereotactic radiosurgery using Gamma Knife technique and may constitute one more option of dosimeter in radiation therapy applications.

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Tissue-equivalent gel for non-invasive spatial radiation dose measurements

Cited by 68 publications

References 7 publications

6 MV wedge photon beam profiles with the fricke xylenol gel dosimeter

6 MV wedge photon beam profiles with the fricke xylenol gel dosimeter

Viabilidade De Novas Formulações Do Dosímetro Químico Fricke Gel

A dosimetric evaluation of tissue equivalent phantom prepared using 270 Bloom gelatin for absorbed dose imaging in Gamma knife radiosurgery

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