Tissue Reactions to Cog Structure and Pure Gold in Lifting Threads: A Histological Study in Rats

Kurita, Masanori; Matsumoto, Daisuke; Kato, Harunosuke; Araki, Jun; Higashino, Takuya; Fukushima, Takashi; Takasu, Katsuya

doi:10.1177/1090820x11398474

Cited by 28 publications

(17 citation statements)

References 14 publications

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“…In an in vivo study, longer, thicker mono or cog threads have more tensile strength, and thicker myofibroblast formation was observed around the cog thread than around the mono thread. 17 , 18 …”

Section: Discussionmentioning

confidence: 99%

Effect of thread embedding acupuncture for facial wrinkles and laxity: a single-arm, prospective, open-label study

Yun

Choi

2017

Integrative Medicine Research

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BackgroundThere is a growing trend for patients to seek the least invasive treatments with less risk of complications and downtime for facial rejuvenation. Thread embedding acupuncture has become popular as a minimally invasive treatment. However, there is little clinical evidence in the literature regarding its effects.MethodsThis single-arm, prospective, open-label study recruited participants who were women aged 40–59 years, with Glogau photoaging scale III–IV. Fourteen participants received thread embedding acupuncture one time and were measured before and after 1 week from the procedure. The primary outcome was a jowl to subnasale vertical distance. The secondary outcomes were facial wrinkle distances, global esthetic improvement scale, Alexiades–Armenakas laxity scale, and patient-oriented self-assessment scale.ResultsFourteen participants underwent thread embedding acupuncture alone, and 12 participants revisited for follow-up outcome measures. For the primary outcome measure, both jowls were elevated in vertical height by 1.87 mm (left) and 1.43 mm (right). Distances of both melolabial and nasolabial folds showed significant improvement. In the Alexiades–Armenakas laxity scale, each evaluator evaluated for four and nine participants by 0.5 grades improved. In the global aesthetic improvement scale, improvement was graded as 1 and 2 in nine and five cases, respectively. The most common adverse events were mild bruising, swelling, and pain. However, adverse events occurred, although mostly minor and of short duration.ConclusionIn this study, thread embedding acupuncture showed clinical potential for facial wrinkles and laxity. However, further large-scale trials with a controlled design and objective measurements are needed.

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Section: Discussionmentioning

confidence: 99%

Effect of thread embedding acupuncture for facial wrinkles and laxity: a single-arm, prospective, open-label study

Yun

Choi

2017

Integrative Medicine Research

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“…The PDO thread diameter in the tissues decreased by 12.5% (3 months) and 87.5% (6 months), and most patients (87%) who underwent PDO thread lifting were considerably satisfied with their outcomes even after 24 months post-operatively [7].…”

Section: Discussionmentioning

confidence: 92%

Immediate treatment of botulinum toxin type A-induced brow ptosis with polydioxanone cog thread insertion

Kang¹,

Chai

2017

J Cosmet Med

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Background: Botulinum toxin is most commonly used as a safe cosmetic injectable to improve dynamic wrinkles. However, side effects still occur. Among them, brow ptosis is known to occur relatively infrequently. The condition is self-limiting; however, for about 3 months post-injection, the patient must endure related uncomfortable symptoms. Several methods have been recommended to prevent this complication; however, no treatment has been developed to improve such symptoms instantly. Currently, various processed threads, such as polydioxanone (PDO), are widely used for facial rejuvenation; PDO thread is bio-absorbable.Objective: The authors performed brow lifting using a cogged PDO thread to improve uncomfortable symptoms associated with brow ptosis. Methods:In total, 14 PDO threads with multi-bidirectional cogs (two 1.0 threads, with lengths of 9.0 cm each, and twelve 1.0 threads, with lengths of 6.0 cm each) were placed in 7 rows, which were inserted into the superficial fat layer and deep fat layer (dual plan insertion) separately, at approximately 1.0-cm intervals.Results: Following the use of the thread, the positions of the left and right eyebrows were observed to have slightly increased by an average of 1.43±0.65 mm and 1.7±0.9 mm after two weeks, respectively; the patients indicated a high degree of satisfaction with immediate improvement of the uncomfortable symptoms. Conclusion:It is suggested that PDO thread brow lifting would be a reliable procedure to immediately treat botulonum-toxin induced brow ptisos noninvasively.

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“…In recent reports, a fibrous capsule was shown to encompass the implanted thread first, and the dermal component increased afterwards. 4,5 We suspect that the immediate lifting effect from the mechanical anchorage is sequentially fortified with the biomechanical force of facial animation.…”

Section: Editormentioning

confidence: 99%

“…3 Research on JAK inhibitors that target the immune system for alopecia areata is underway. 5 The efficacy of existing immunosuppressive agents such as cyclosporine remains controversial. 6 Clinical information on the efficacy of oral tacrolimus (FK506) for alopecia areata is entirely absent.…”

Section: Successful Hair Regrowth In An Acute Diffuse Form Of Alopecimentioning

confidence: 99%

Evaluation of a novel thread‐lift for the improvement of nasolabial folds and cheek laxity

Kim

Seo

et al. 2016

Acad Dermatol Venereol

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Tissue Reactions to Cog Structure and Pure Gold in Lifting Threads: A Histological Study in Rats

Abstract: The combination of cog structure and pure gold coating was evaluated for the first time in this study and results suggest that the gold-coated cog thread has clinical potential.

Cited by 28 publications

References 14 publications

Effect of thread embedding acupuncture for facial wrinkles and laxity: a single-arm, prospective, open-label study

Effect of thread embedding acupuncture for facial wrinkles and laxity: a single-arm, prospective, open-label study

Immediate treatment of botulinum toxin type A-induced brow ptosis with polydioxanone cog thread insertion

Evaluation of a novel thread‐lift for the improvement of nasolabial folds and cheek laxity

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