Titanium Dental Implants in Compromised Conditions: Need for Enhanced Bioactivity and Therapy

Kocak-Oztug, Necla Asli; Ravali, Ece Irem

doi:10.1007/978-3-031-21565-0_2

Cited by 2 publications

(1 citation statement)

References 142 publications

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“…Materials with specific mechanical qualities, such as drug-controlled release, biodegradability, and mechanical stability, are needed for these devices. Polymers such as PLA, PGA, or copolymers (PLGA) are often used in drug delivery [229]. v Prosthetics: Utilizing polymers and their composites, prosthetics are manufactured, including artificial hands, feet, and limbs.…”

Section: Mechanical Applicationsmentioning

confidence: 99%

Promising New Horizons in Medicine: Medical Advancements with Nanocomposite Manufacturing via 3D Printing

Li,

Khan,

Chen

et al. 2023

Polymers

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Three-dimensional printing technology has fundamentally revolutionized the product development processes in several industries. Three-dimensional printing enables the creation of tailored prostheses and other medical equipment, anatomical models for surgical planning and training, and even innovative means of directly giving drugs to patients. Polymers and their composites have found broad usage in the healthcare business due to their many beneficial properties. As a result, the application of 3D printing technology in the medical area has transformed the design and manufacturing of medical devices and prosthetics. Polymers and their composites have become attractive materials in this industry because of their unique mechanical, thermal, electrical, and optical qualities. This review article presents a comprehensive analysis of the current state-of-the-art applications of polymer and its composites in the medical field using 3D printing technology. It covers the latest research developments in the design and manufacturing of patient-specific medical devices, prostheses, and anatomical models for surgical planning and training. The article also discusses the use of 3D printing technology for drug delivery systems (DDS) and tissue engineering. Various 3D printing techniques, such as stereolithography, fused deposition modeling (FDM), and selective laser sintering (SLS), are reviewed, along with their benefits and drawbacks. Legal and regulatory issues related to the use of 3D printing technology in the medical field are also addressed. The article concludes with an outlook on the future potential of polymer and its composites in 3D printing technology for the medical field. The research findings indicate that 3D printing technology has enormous potential to revolutionize the development and manufacture of medical devices, leading to improved patient outcomes and better healthcare services.

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Section: Mechanical Applicationsmentioning

confidence: 99%

Promising New Horizons in Medicine: Medical Advancements with Nanocomposite Manufacturing via 3D Printing

Li,

Khan,

Chen

et al. 2023

Polymers

View full text Add to dashboard Cite

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Inflammatory or Reparative? Tuning Macrophage Polarization Using Anodized Anisotropic Nanoporous Titanium Implant Surfaces

Moon,

Gulati,

et al. 2024

Small Science

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Modulating macrophage phenotype based on implant surface characteristics, including topography and chemistry, has been employed to enhance osseointegration and long‐term functional outcomes for titanium (Ti)‐based implants. An excessive and/or prolonged M1 macrophage response can lead to damaging immune‐inflammatory reactions, negatively influencing the fate of the implant, and hence, modulating these responses via nanoscale implant surface modification is an emerging paradigm. Herein, an anodized titanium implant surface based on single‐step electrochemical anodization, with preserved underlying microfeatures and superimposed nanopores (50 and 70 nm), compared with irregular rough and microrough (machined‐like) surfaces, is investigated for its effect on the functions of primary macrophages in vitro. Significantly reduced macrophage proliferation and increased tissue‐reparative M2 phenotype polarization are confirmed for the nanopores, which are more pronounced for 70 nm diameter. Moreover, osteoclastogenesis is reduced while osteogenic differentiation of osteoblasts is enhanced for the nanopores (higher for 70 nm pores). Advanced nanoengineered Ti implants can enhance titanium implant tissue integration by modulating the inflammatory response at the implant–cell interface.

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Titanium Dental Implants in Compromised Conditions: Need for Enhanced Bioactivity and Therapy

Cited by 2 publications

References 142 publications

Promising New Horizons in Medicine: Medical Advancements with Nanocomposite Manufacturing via 3D Printing

Promising New Horizons in Medicine: Medical Advancements with Nanocomposite Manufacturing via 3D Printing

Inflammatory or Reparative? Tuning Macrophage Polarization Using Anodized Anisotropic Nanoporous Titanium Implant Surfaces

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