To the Editor–PVCs and left ventricular function

Chatterjee, Debjit

doi:10.1016/j.hrthm.2010.07.033

Cited by 2 publications

(1 citation statement)

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“…In contrast, the LV dysfunction should persist immediately after successful ablation but improve gradually over time in true PVC-induced cardiomyopathy. 69 There is little evidence at present to recommend treating asymptomatic patients with normal LVEF. The benefit of performing PVC ablation in these patients guided only by a high PVC burden has not yet been demonstrated and can be potentially hazardous.…”

Section: Pharmacotherapy Versus Catheter Ablationmentioning

confidence: 99%

Premature Ventricular Complex-induced Cardiomyopathy

Panizo

Barra

Mellor

et al. 2018

Arrhythmia &Amp; Electrophysiology Review

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Premature ventricular complex-induced cardiomyopathy is a potentially reversible condition in which left ventricular dysfunction is induced by the occurrence of frequent premature ventricular complexes (PVCs). Various cellular and extracellular mechanisms and risk factors for developing cardiomyopathy in this context have been suggested but the exact pathophysiological mechanism remains unclear. The suppression of PVCs is usually indicated in symptomatic patients with frequent PVCs and also those with left ventricular dysfunction. Antiarrhythmic drugs are a useful non-invasive treatment to eliminate PVCs, but the side effect profile, including the risk of pro-arrhythmia, along with suboptimal clinical effectiveness, should be weighed against the usually more effective but not risk-free treatment with catheter ablation. The latter has progressively become first line therapy in many patients with PVC-induced cardiomyopathy and should be particularly considered in specific scenarios.

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Section: Pharmacotherapy Versus Catheter Ablationmentioning

confidence: 99%