Tooth loss in aggressive periodontitis: Results 25 years after active periodontal therapy in a private practice

Bäumer, Amelie; Weber, Dorothea; Staufer, Sebastian; Pretzl, Bernadette; Körner, Gerd; Wang, Yan

doi:10.1111/jcpe.13225

Cited by 19 publications

(42 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Similar results to ours may also be found in a retrospective long‐term study over a period of 25 years in a dental practice setting, who reported an overall tooth loss of 9.5% during SPT, significantly influenced by location/jaw, tooth type, baseline bone loss and abutment function (Bäumer et al., 2020). However, tooth loss was evaluated only in patients diagnosed with aggressive periodontitis.…”

Section: Discussionsupporting

confidence: 90%

“…A direct comparison, for example with the long‐term study of Axelsson et al., 2004, who evaluated tooth loss over a 30‐year‐period on patient level, is aggravated, because of the different statistical approaches. Only few studies document data over 20 years after APT on tooth level (Bäumer et al., 2020; Graetz et al., 2017; Martinez‐Canut, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…Several studies demonstrate the influence of tooth‐related factors on tooth loss (Chambrone & Chambrone, 2006; Dannewitz et al., 2016; König, Plagmann, Rühling, & Kocher, 2002; Matuliene et al., 2008; McGuire & Nunn, 1996; Muzzi et al., 2006; Pretzl, Kaltschmitt, Kim, Reitmeir, & Eickholz, 2008). However, only few have documented the influence of tooth‐related factors over a period of 20 years (Axelsson, Nystrom, & Lindhe, 2004; Bäumer et al., 2020; Graetz et al., 2017; Martinez‐Canut, 2015).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Tooth‐related factors for tooth loss 20 years after active periodontal therapy–A partially prospective study

Rahim-Wöstefeld

Sayed

Weber

et al. 2020

J Clinic Periodontology

Self Cite

View full text Add to dashboard Cite

Aim To assess factors contributing to tooth loss 20 years after active periodontal therapy (APT) on tooth level. Materials and Methods After an initial retrospective analysis 10 years after APT, patients were monitored for 10 more years. At clinical re‐evaluation 20 years after APT, tooth‐related factors (tooth type, location, bone loss, furcation involvement, abutment status) and patient‐related factors (gender, smoking, adherence) were investigated. Descriptive statistical analysis and a mixed logistic regression analysis were performed with tooth loss as primary outcome variable. Results The study included 69 patients (42 female/27 male). 39 patients were non‐adherent (56.5%), and 11 were active smokers (15.9%). A total of 198 out of 1611 teeth were lost. Tooth loss was significantly highest (p < .01) in molars (21.1%), multi‐rooted teeth with furcation involvement (23.5%) and abutment teeth (fixed: 27.6%, removable: 36.4%). 37.6% of teeth with initial bone loss >60% were lost during 20 years. Adherent patients showed less frequent tooth loss than non‐adherent patients (OR 0.371; p < .01). Conclusion Even teeth with an initial bone loss over 60% could be retained in approximately two thirds for 20 years. This should be kept in mind when assigning prognosis and establishing a treatment plan.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Tooth‐related factors for tooth loss 20 years after active periodontal therapy–A partially prospective study

Rahim-Wöstefeld

Sayed

Weber

et al. 2020

J Clinic Periodontology

Self Cite

View full text Add to dashboard Cite

show abstract

“…The severity of periodontal disease and the associated risk of tooth loss are higher in molars than in non‐furcated teeth (Bäumer et al., 2019; Hirschfeld & Wasserman, 1978; Papapanou, Wennstrom, & Grondahl, 1989). Therefore, correct diagnosis of furcation involvement (FI) is crucial for both prognosis estimation and optimization of treatment strategies (Avila‐Ortiz, De Buitrago, & Reddy, 2015; Scarfe, Azevedo, Pinheiro, Priaminiarti, & Sales, 2017).…”

Section: Introductionmentioning

confidence: 99%

In vivo accuracy of dental magnetic resonance imaging in assessing maxillary molar furcation involvement: A feasibility study in humans

Juerchott

Sohani²,

Schwindling

et al. 2020

J Clinic Periodontology

View full text Add to dashboard Cite

Aim To investigate the accuracy and reliability of dental magnetic resonance imaging (dMRI) in assessing maxillary molar furcation involvement (FI). Material and Methods In this prospective study, 22 patients with severe periodontitis underwent cone‐beam computed tomography (CBCT) and dMRI. For 192 furcation entrances, the degree of horizontal FI was assessed by two independent observers on both modalities. Results of dMRI were compared with CBCT (reference modality) to assess the accuracy of dMRI. Cohen's kappa (κ), sensitivity and specificity were calculated for FI classification. Bland–Altman analysis and the Kruskal–Wallis test were used to evaluate measurement accuracy of dMRI. Results Based on CBCT findings, 93 furcation entrances revealed FI (degree I/II/III: 35/19/39). Intra‐ and inter‐reader agreement was excellent for both modalities (κ‐range: 0.884 to 0.933). dMRI measurements showed high agreement with CBCT (bias: 0.17 mm; 95% limits of agreement: −1.05 to 1.38 mm), and measurement accuracy did not differ among different degrees of FI (p = .67). For FI detection, sensitivity and specificity of dMRI were 98% and 99%. For FI classification, sensitivity values of dMRI were 89%/84%/100% for degree I/II/III. Conclusions Compared to CBCT (non‐invasive gold standard), dMRI demonstrates high accuracy and reliability in evaluating the degree of FI in maxillary molars.

show abstract

“…На сегодняшний день, несмотря на проведенные многочисленные исследования в этом направлении, воспалительные заболевания тканей пародонта остаются одной из наиболее сложных и нерешенных проблем современной стоматологии. Общее количество людей с данной патологией прогрессивно увеличивается во всех возрастных группах, особенно среди людей трудоспособного возраста, и даже детей [1,2], а последствия данного патологического процесса многогранные и непредсказуемые [3]. Одним из патогенетических звеньев генерализованного пародонтита является нарушение в дыхательной цепи митохондрий [4].…”

unclassified

Dynamics of Mitochondrial Transmembrane Potential Changes in Blood Monocytes in Conditions of Development and Course of Experimental Periodontitis and the Effect of Korvityn on it

Demkovych¹,

Machogan²

2020

Ukr. ž. med. bìol. sportu

View full text Add to dashboard Cite

Inflammatory diseases of periodontal tissues remain one of the most complex and unresolved problems of modern dentistry. The most important internal stimulus for triggering apoptosis is DNA damage in response to various factors (including reactive oxygen species). Mitochondrial transmembrane potential (Δψm) is generated by the electrochemical gradient of protons on both sides of the membrane and is closely related to the functioning of mitochondria, its support is provided by the processes of electron transfer in the respiratory chain. The purpose of our study was to elucidate the pathogenetic role of changes in mitochondrial transmebranic potential in the dynamics of the inflammatory response in experimental bacterial-immune periodontitis and the effects of quercetin (Korvityn) on it. Material and methods. The study was performed on white clinically healthy rats. Experimental bacterial-immune periodontitis in experimental animals was induced by injection of a mixture of microorganisms diluted with egg protein into the tissues of the periodontal complex. Quercetin was administered by intramuscular injection for correction. Evaluation of changes in mitochondrial transmembrane potential of leukocytes was performed by flow cytofluorimetry. Results and discussion. In experimental bacterial-immune periodontitis, the percentage of cells with reduced mitochondrial transmembrane potential among blood monocytes significantly increased. In animals on the 7th day of the study, the number of cells with reduced mitochondrial transmembrane potential among blood monocytes increased significantly compared with the control group. For the next study period (14th day), the number of cells with reduced ∆ψm decreased compared to the 7th day of the experiment. Having analyzed the data of mitochondrial transmembrane potential of blood monocytes on the 30th day of the experiment, we noted that they decreased relative to those obtained on the 14th day of the study, indicating profound oxidative imbalance in cells and destabilization of the mitochondrial membrane. The use of quercetin led to a decrease in the values compared to the data of animals with our simulated pathology on the 14th day, the experiment without the introduction of flavonol, but they remained significantly higher than the control group of animals. Conclusion. Flavonol (Korvityn) quercetin reduced mitochondrial transmembrane potential in experimental bacterial-immune periodontitis, which was evidence by stabilization and attenuation of the inflammatory process

show abstract

Tooth loss in aggressive periodontitis: Results 25 years after active periodontal therapy in a private practice

Cited by 19 publications

References 26 publications

Tooth‐related factors for tooth loss 20 years after active periodontal therapy–A partially prospective study

Tooth‐related factors for tooth loss 20 years after active periodontal therapy–A partially prospective study

In vivo accuracy of dental magnetic resonance imaging in assessing maxillary molar furcation involvement: A feasibility study in humans

Dynamics of Mitochondrial Transmembrane Potential Changes in Blood Monocytes in Conditions of Development and Course of Experimental Periodontitis and the Effect of Korvityn on it

Contact Info

Product

Resources

About