Abstract:Abstract:The present work studies the effects of topical application of nucleotides on rabbit tear lysozyme levels. Lysozyme values were determined by the diffusion in Agar method described by van Bijsterveld in 1974, and the protein amount was obtained by measuring the inhibitory halos around a Whatman nº1 paper disc of 5 mm in diameter. The tested nucleotides were UTP, Ap 4 A and Up 4 U. These compounds were topically instilled in a single-dose in one eye (with the contralateral eye as a control) and the lys… Show more
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