Topical Steroids Are Effective in the Treatment of Idiopathic Granulomatous Mastitis

Abstract

Topical steroids seem to be effective in the treatment of IGM characterized by skin changes. Prospective clinical studies would be useful in determining the clinical efficacy of topical steroids in the treatment of IGM.

Cystic neutrophilic granulomatous mastitis: an update

“…DeHertogh et al first proposed the use of prednisolone for the treatment of granulomatous mastitis in 1980 97. Additional reports demonstrate effective response to steroids 98–101. Some studies show positive serological tests used in autoimmune disorders in patients with GLM.…”

Factors related to recurrence of idiopathic granulomatous mastitis: what do we learn from a multicentre study?

“…Recurrence may be observed despite broad surgical excision in IGM. The IGM recurrence rate varies between 5% and 50% according to the literature . Post‐excision recurrence may be as high as 50% .…”

The evaluation of the efficacy of local steroid administration in idiopathic granulomatous mastitis: The preliminary results

“…Altıntoprak et al performed steroid treatment as a topical application of a steroid ointment for a mean duration of 8.2 weeks in 28 IGM patients. Recurrence was observed in only three patients whereas no steroid‐related side effect was detected in any patient . Even though it was radiologically shown in the study conducted by Gündüz et al that local steroid applied topically over the breast skin was effective on breast parenchyma, in overweight patients with large breast tissues, and in deeply located lesions, the success of local steroid in treating parenchymal lesions would be limited.…”