Topische Anwendung von Heilpflanzen zur Unterstützung der Wundheilung

Embacher, Karin; Zilkowski, Ilona; Turek, Claudia; Stintzing, Florian C.

doi:10.1055/a-1406-4785

Cited by 2 publications

(1 citation statement)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Echter Wundklee) belongs to the family Fabaceae. It is a perennial herb native throughout Europe and Northern Africa and is nowadays mostly used in cosmetics [34,35]. In the VOLKSMED database, this plant has 42 entries.…”

Section: Anthyllis Vulnerariamentioning

confidence: 99%

VOLKSMED Database: A Source for Forgotten Wound Healing Plants in Austrian Folk Medicine

Eichenauer,

Saukel,

Glasl

2024

Planta Med

View full text Add to dashboard Cite

The global increase in the incidence of wounds is concerning and fuels the search for new treatment options. The use of traditional medicinal plants in wound healing represents an appreciated available therapeutic possibility. This work introduces the VOLKSMED database, which contains plants and other materials used in Austrian folk medicine, either as monographs or mixtures. This work focuses on the monographs of the database. Concerning wound healing, Hypericum sp., Arnica montana, Calendula officinalis, Plantago sp., and Malva sp. are the most commonly used plants. The focus of this paper is set on selected lesser-known plants (Abies alba, Anthyllis vulneraria, Brassica sp., Gentiana sp., Larix decidua, Picea abies, Sambucus sp., Sanicula europaea) and their status quo in literature concerning wound healing. A systematic search using the databases SciFinder, SCOPUS, and PubMed yielded substantial evidence for the wound healing potential of Brassica sp., Gentiana sp., the Pinaceae A. abies, L. decidua, and P. abies, as well as Sambucus nigra. In vivo and clinical studies substantiate their use in Austrian folk medicine. According to the literature, especially A. vulneraria, Sambucus racemosa, and S. europaea would be worth investigating in-depth since data concerning their wound healing effects – even though scarce – are convincing. In conclusion, the VOLKSMED database contains promising opportunities for further treatment options in the field of wound healing. Future research should consider the listed plants to support their traditional use in Austrian folk medicine and possibly promote the implementation of old knowledge in modern medicine.

show abstract

Section: Anthyllis Vulnerariamentioning

confidence: 99%

VOLKSMED Database: A Source for Forgotten Wound Healing Plants in Austrian Folk Medicine

Eichenauer,

Saukel,

Glasl

2024

Planta Med

View full text Add to dashboard Cite

show abstract

Comparison of Aqueous and Lactobacterial-Fermented Mercurialis perennis L. (Dog’s Mercury) Extracts with Respect to Their Immunostimulating Activity

et al. 2023

View full text Add to dashboard Cite

Lactic acid (LA) fermentation of dog’s mercury (M. perennis L.) herbal parts was investigated in samples inoculated with either Lactobacteria (Lactobacillus plantarum and Pediococcus pentosaceus, LBF) or whey (WF). Depending on fermentation time, LA concentrations were monitored in a range of 3.4–15.6 g/L with a concomitant pH decline from 6.5 to 3.9. A broad spectrum of cinnamic acids depsides containing glucaric, malic and 2-hydroxyglutaric acids along with quercetin and kaempferol glycosides were detected by LC-DAD-ESI-MSn. Moreover, in this study novel constituents were also found both in unfermented and fermented extracts. Furthermore, amino acids and particular Lactobacteria metabolites such as biogenic amines (e.g., putrescine, 4-aminobutyric acid, cadaverine) and 5-oxoproline were assigned in WF extracts by GC-MS analysis after silylation. Enhanced NFκB and cytokine expression (IL-6, TNFα, IL-8 and IL-1β) was induced by all extracts, both non-fermented and fermented, in NFκB-THP1 reporter cells, showing a concentration-dependent immunostimulatory effect. The WF extracts were tested for micronuclei formation in THP1 cells and toxicity in luminescent bacteria (V. fischeri), whereby no mutagenic or toxic effects could be detected, which corroborates their safe use in pharmaceutical remedies.

show abstract

Topische Anwendung von Heilpflanzen zur Unterstützung der Wundheilung

Cited by 2 publications

References 78 publications

VOLKSMED Database: A Source for Forgotten Wound Healing Plants in Austrian Folk Medicine

VOLKSMED Database: A Source for Forgotten Wound Healing Plants in Austrian Folk Medicine

Comparison of Aqueous and Lactobacterial-Fermented Mercurialis perennis L. (Dog’s Mercury) Extracts with Respect to Their Immunostimulating Activity

Contact Info

Product

Resources

About