Toradol following Breast Surgery: Is There an Increased Risk of Hematoma?

Nguyen, Bach T.; Barta, Ruth J.; Stewart, Christine E.; Heinrich, Cherrie A.

doi:10.1097/prs.0000000000004361

Cited by 34 publications

(14 citation statements)

References 7 publications

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“…It also pose great challenges to the clinicians due to unfavorable side effect profiles, abuse and tolerance ( 101 ). Ketorolac tromethamine (Toradol), a non-steroidal anti-inflammatory drug, is used frequently due to its success in relieving postoperative pain and reducing the need for narcotics ( 102 ). Recent study showed that the non-steroidal anti-inflammatory drugs (NSAIDs) are not associated with increased postoperative bleeding and have fewer complications than opioids ( 103 ).…”

Section: Measures To Prevent and Improve Postoperative Sleep Disturbamentioning

confidence: 99%

Sleep Disturbances After General Anesthesia: Current Perspectives

2020

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The purpose of this article is to review (1) sleep mechanism under general anesthesia, harmful effects of postoperative sleep disturbances; (2) risk factors associated with postoperative sleep disturbances; (3) measures to prevent and improve postoperative sleep disturbances. General anesthesia changes the postoperative sleep structure especially in elderly patients after major surgery and results in a high incidence rate of sleep disturbances. Sleep disturbances produce harmful effects on postoperative patients and lead to a higher risk of delirium, more cardiovascular events, and poorer recovery. Some researchers do propose non-pharmacological treatments such as attention to environmental and psychological factors, application of electroacupuncture (EA) technology and pharmacological treatments are helpful, but larger high-quality clinical trials with longer following-up are needed to further investigate the efficacy and safety.

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Section: Measures To Prevent and Improve Postoperative Sleep Disturbamentioning

confidence: 99%

Sleep Disturbances After General Anesthesia: Current Perspectives

2020

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“…A study of 168,990 patients undergoing nasal surgery (septoplasty, rhinoplasty, or inferior turbinate reduction) investigating the impact of NSAIDs on postoperative bleeding found no association between NSAIDs and increased postoperative complications including epistaxis, septal hematoma, emergency room visits, hospital readmission, and 30-day reoperation 39. Another study investigating the impact of ketorolac tromethamine (Toradol) on hematoma formation in breast surgery concluded that there was no statistically significant difference in hematoma formation due to ketorolac 40…”

Section: Discussionmentioning

confidence: 99%

Perioperative Medication Management in Elective Plastic Surgery Procedures

Chaya

Colon

Boczar

et al. 2023

Journal of Craniofacial Surgery

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Background: Perioperative medication management is vital to maintain patient safety while under anesthesia, as well as to avoid postoperative complications. Plastic surgeons make daily decisions on whether to ask a patient to stop taking medication before their surgery. These important decisions can affect bleeding risk, wound healing, and interactions with anesthetics, which can range from minor to life-threatening. Current plastic surgery literature lacks a comprehensive review of perioperative medication management, with existing reports focusing on specific procedures and specific medication classes. Methods: A PubMed database search was conducted for articles through July 2021. The bibliographies of included studies were also examined for articles not acquired in the initial search queries. The authors included studies on medication usage and perioperative guidance in patients undergoing elective plastic surgery procedures. The authors excluded studies unrelated to plastic surgery and studies where the medications were used as an intervention. Abstracts, animal studies, studies involving the pediatric population, and book chapters were also excluded, as well as articles not published in English. Results: A total of 801 papers were identified by our search terms. After title and abstract screening, 35 papers were selected for full-text review. After full-text review, 20 papers were selected for inclusion, with an additional 6 papers from cited references added. Of the 26 papers, 6 papers discussed psychotropic drugs, 6 papers discussed medications affecting hemostasis, 4 papers discussed hormone-containing medications, 3 papers discussed antilipid medications, 2 papers discussed antihypertensive medications, 2 papers discussed herbal supplements, 1 paper discussed both psychotropic and herbal supplements, 1 paper discussed medications affecting wound healing, and 1 paper discussed rheumatologic medications. A summary of those recommendations was then compiled together. Conclusions: The perioperative medication management in elective plastic surgery procedures remains a complex and multidisciplinary process. It is important to manage these patients in a case-by-case manner and to consult a specialist when necessary. Careful medication reconciliation is essential to decrease the likelihood of adverse outcomes and interactions with perioperative anesthetics.

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“…Отечественные и зарубежные авторы сообщают о частом развитии гематом в послеоперационном периоде после различных хирургических вмешательств на молочной железе. По данным литературы, факторами риска развития гематом в послеоперационном периоде являются курение, ожирение, увеличение груди, лечение антикоагулянтами и пожилой возраст [20,21]. Как правило, ранние клинически значимые послеоперационные гематомы развиваются в течение первых 12-48 ч после операции, реже гематома появляется через несколько дней или недель после оперативного вмешательства.…”

Section: Discussionunclassified

Early postoperative complications in patients operated on for breast cancer using different surgical techniques

Исмагилов

Karasev²

2021

Opuholi ženskoj reproduktivnoj sistemy

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Background. Given the steady and intense increase in the incidence of breast cancer, the problem of the development of early complications of reconstructive operations, depending on the characteristics of surgery, remains urgent.Objective: to analyze the characteristics of the early postoperative period in patients operated on for breast cancer using different surgical techniques.Materials and methods. A comparative analysis of clinical examination data was carried out, as well as laboratory and instrumental diagnostic methods for 353 women with stage I to IIIA breast cancer after various surgical treatment options and 40 patients after mammoplasty.Results and conclusions. It has been shown that neither single-step nor delayed reconstructive operations after radical mastectomy increase the incidence of complications in the early postoperative period. Single-step breast reconstruction with the help of an expander can be used in patients with I–IIIA stages of the tumor process.

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Toradol following Breast Surgery: Is There an Increased Risk of Hematoma?

Abstract: Therapeutic, III.

Cited by 34 publications

References 7 publications

Sleep Disturbances After General Anesthesia: Current Perspectives

Sleep Disturbances After General Anesthesia: Current Perspectives

Perioperative Medication Management in Elective Plastic Surgery Procedures

Early postoperative complications in patients operated on for breast cancer using different surgical techniques

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