Torsional force applied to the tibia of living lambs in an attempt to change the bone rotational axis

Volpon, José Batista; Falcai, Maurício José; Moro, Carlos; Leal, Daniel Mendes

doi:10.1590/s0102-86502014000300008

Cited by 2 publications

(12 citation statements)

References 18 publications

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“…A total of 14 studies (10 preclinical ( 3 , 4 , 9 , 10 , 11 , 12 , 17 , 18 , 19 , 20 ), 3 clinical ( 5 , 13 , 14 ), and 1 review ( 16 )) were included that examined guided growth for rotational deformities.…”

Section: Resultsmentioning

confidence: 99%

“…Two ( 12 , 19 ) of the eight in vivo preclinical studies used an external device, with pins on either side of the growth plate, that relied on manually applied, external torque to achieve rotation of the bones. One ( 17 ) was a case report in which the device spanned the stifle joints of a dog and therefore the achieved rotation, presumably, also did occur at the level of the joint.…”

Section: Resultsmentioning

confidence: 99%

“…Five ( 4 , 9 , 11 , 12 , 20 ) of the preclinical, in vivo studies reported relevant approval by institutional or ethics committee. For the clinical studies, only Paley et al ( 14 ) reported approval by their institutional review board.…”

Section: Resultsmentioning

confidence: 99%

“…In 2013, Arami et al showed that by placing plates in an oblique orientation over the physis, it is possible to induce rotational guided growth in rabbits ( 4 ). Since then, similar studies ( 9 , 10 , 11 , 12 ) have shown similar promising results, but there are still many questions left unanswered.…”

Section: Introductionmentioning

confidence: 88%

“…Furthermore, reference lists of all included studies were screened. Together this resulted in the inclusion of additional seven studies ( 12 , 13 , 14 , 17 , 18 , 19 , 20 ) ( Fig. 1 ).…”

Section: Methodsmentioning

confidence: 99%

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Correction of rotational deformities in long bones using guided growth: a scoping review

Halloum,

Kold,

Rölfing

et al. 2024

EFORT Open Reviews

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Purpose The objective of this scoping review was to describe the extent and type of evidence of using guided growth to correct rotational deformities of long bones in children. Methods This scoping review was conducted in accordance with the JBI methodology for scoping reviews. All published and unpublished studies investigating surgical methods using guided growth to perform gradual rotation of long bones were included. Results Fourteen studies were included: one review, three clinical studies, and ten preclinical studies. In the three clinical studies, three different surgical methods were used on 21 children. Some degree of rotation was achieved in all but two children. Adverse effects reported included limb length discrepancy (LLD), knee stiffness and rebound of rotation after removal of tethers. Of the ten preclinical studies, two were ex vivo and eight were in vivo. Rotation was achieved in all preclinical studies. Adverse effects reported included implant extrusions, LLD, articular deformities, joint stiffness and rebound of rotation after removal of tethers. Two of the studies reported on histological changes. Conclusions All studies conclude that guided growth is a potential treatment for rotational deformities of long bones. There is great variation in animal models and surgical methods used and in reported adverse effects. More research is needed to shed light on the best surgical guided growth method, its effectiveness as well as the involved risks and complications. Based on current evidence the procedure is still to be considered experimental. Level of evidence 4

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 88%

“…Furthermore, reference lists of all included studies were screened. Together this resulted in the inclusion of additional seven studies ( 12 , 13 , 14 , 17 , 18 , 19 , 20 ) ( Fig. 1 ).…”

Section: Methodsmentioning

confidence: 99%

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