2022
DOI: 10.3389/fphar.2022.888522
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Total Barley Maiya Alkaloids Prevent Increased Prolactin Levels Caused by Antipsychotic Drugs and Reduce Dopamine Receptor D2 via Epigenetic Mechanisms

Abstract: Background: The dopamine D2 receptor (DRD2) plays an important role in the increased prolactin (PRL) levels associated with the pathogenesis of antipsychotic drugs (ADs). Elevated prolactin levels can affect people’s quality of life. Maiya alkaloids has been used to treat diseases associated with high PRL levels. Maiya, is a processed product of the mature fruits of Hordeum vulgare L. (a gramineous plant) after sprouting and drying and also a common Chinese herbal drug used in the clinic, is traditionally used… Show more

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Cited by 4 publications
(1 citation statement)
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“…Alternatively, vitamin B6 is often recommended, which has been reported to lower prolactin levels by influencing levels of dopamine. Additionally, some natural treatments that lower prolactin levels are often recommended, such as reducing alcohol intake, reducing stress with yoga or meditation, or taking herbal medicine called chaste berry (Vitex agnus-castus) [ 62 ].…”
Section: Prl and Neuropsychiatric Disordersmentioning
confidence: 99%
“…Alternatively, vitamin B6 is often recommended, which has been reported to lower prolactin levels by influencing levels of dopamine. Additionally, some natural treatments that lower prolactin levels are often recommended, such as reducing alcohol intake, reducing stress with yoga or meditation, or taking herbal medicine called chaste berry (Vitex agnus-castus) [ 62 ].…”
Section: Prl and Neuropsychiatric Disordersmentioning
confidence: 99%