Total-Body PET/CT: Current Applications and Future Perspectives

Feasibility of Acquisitions Using Total-Body PET/CT with an Ultra-Low 18F-FDG Activity

“…We hypothesized that the additional uptake time (with a maximum of 15 minutes) will be more noticeable when the acquired counts were reduced. The effect on the increased accumulation of FDG in the malignant lesions will be more significant and thus increase the lesion SUV, as observed in the time-activity curves in previous studies (16,17). Additionally, a discrepancy between visual and quantitative analysis was found.…”

New PET technologies – embracing progress and pushing the limits

“…Total-body PET is a transformative technology that changes the equation [57][58][59][60][61]. The use of detectors that cover the entire human body not only increases the imaging field of view but, by increasing the solid angle coverage, increases detection efficiency, such that for a given administered dose and acquisition time, roughly 40-fold more events are collected from the whole body.…”

[18F]FDG-PET Evaluation of Spinal Pathology in Patients in Oncology: Pearls and Pitfalls for the Neuroradiologist

“…With their increased axial FOV, these scanners use increased detection efficiency and scanner sensitivity to considerably improve the signal-to-noise ratio and temporal resolution, all while using a lower radiopharmaceutical dose, which can be specifically useful in determining the extent of disease in the spine and spinal cord. 59,60 However, a major limitation for institutions outside of large research institutions remains the cost of these scanners, particularly the scintillation material, as well as data storage and processing concerns. 61…”