Total flavonoid content and formulation antioxidant cream stem of <i>jatropha multifida</i> l.

Franyoto, Yuvianti Dwi; Kusmita, Lia; Mutmainah, _; Angrena, Riega Demma

doi:10.1088/1742-6596/1025/1/012130

Cited by 4 publications

(3 citation statements)

References 11 publications

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“…The concentration of flavonoids (TFC) and carotenoids (TCC) in 100 g of 1 and 10% BGCE cream were 2.74 mg (TFC) and 23.1 µg (TCC) and 27.4 mg (TFC) and 231.0 µg (TCC), respectively. These concentrations are consistent with those that are typically found in studies on antioxidant creams based on natural extracts of flavonoids or carotenoids [51,52]. The samples were then subjected to accelerating ageing for 90 days (40 • C, 75% humidity, dark).…”

Section: Cream Preparationsupporting

confidence: 86%

Natural Deep Eutectic Solvents as a Novel Bio-Based Matrix for Ready-to-Use Natural Antioxidants-Enriched Ingredients: Extraction and Formulation Optimization

Boudesocque-Delaye,

Ardeza,

Verger

et al. 2024

Cosmetics

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The escalating consumer demand for sustainable cosmetic ingredients poses distinct challenges, particularly concerning their stability within the final formulation. Although natural resources offer a pool of antioxidant molecules with diverse structures and polarities, achieving stabilization combined with a comprehensive antioxidant profile often proves incompatible with practical preformulation considerations. Notably, Calendula, which is rich in both polar (glycosylated flavonoids) and nonpolar (carotenoids) antioxidants, is a standout candidate. Nevertheless, the market lacks an ingredient embodying this diversity, primarily due to the limited polarity range of available usable solvents. Natural deep eutectic solvents (NaDESs) emerge as a promising solution. This study explores NaDES technology with the goal of developing a unique Calendula extract enriched in both polarities of antioxidants, a composition that is unattainable with traditional solvents. A screening of 12 NaDESs with varying polarities highlighted a NaDES based on betaine and glycerol as particularly effective, outperforming ethanol. Leveraging response surface methodology, an optimal mechanical stirring procedure for extraction was identified. The resulting extract showed a total flavonoid content of 45.42 ± 0.85 mg eq rutin/g of biomass and a total carotenoid content of 383.54 ± 4.73 µg/g biomass. It was then incorporated into a sustainable cream (1% and 10%wt) using an innovative mixing technology. The resulting creams demonstrated stability over 90 days, with no significant deviations in pH or rheological properties compared to the control, and a droplet size that was inferior to 10 µm. This study lays the foundation for pioneering natural antioxidant cocktail-loaded ingredients that are suitable for eco-friendly cosmetic formulations, substantiating the viability of integrating environmentally friendly ingredient-based solvents.

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Section: Cream Preparationsupporting

confidence: 86%

Natural Deep Eutectic Solvents as a Novel Bio-Based Matrix for Ready-to-Use Natural Antioxidants-Enriched Ingredients: Extraction and Formulation Optimization

Boudesocque-Delaye,

Ardeza,

Verger

et al. 2024

Cosmetics

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“…Total flavonoid content and formulation of antioxidant cream stem from jatropha multifida (30) English…”

Section: Characterization Of the Biological Activities Of J Multifidamentioning

confidence: 99%

Biological activities: anti-infectious, antioxidant and healing of the vegetable species Jatropha multifida

et al. 2021

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Objective: to investigate the biological activities of interest to the health of Jatropha multifida plant species in published scientific literature. Methods: this is an integrative review, with searches between May and June 2019, using the descriptors, combined through the Boolean operator AND, Jatropha multifida, anti-infective agents, wound healing, cytotoxicity and antioxidants, in LILACS, BDENF, MEDLINE, SciFinder, Web of Science and Scopus databases and in the virtual libraries SciELO and ScienceDirect. Results: twelve publications were retrieved that showed nine biological activities. The antioxidant activity was reported in 04 (33.33%) studies; antimicrobial and anticancer, addressed by 03 (25%) and 02 (16.66%); anti-inflammatory, anti-melanin deposition, healing, antiophidic, purgative and anti-influenza, seen in 01 (8.33%) each. Final considerations: although scarce, the published scientific production highlights the biological potential of J. multifida and supports the need for further studies.

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“…Penulis Garretson, et al (2018) melaporkan, dengan kombinasi senyawa flavonoid dan non falvanoid lainnya memiliki hubungan penting dalam hal rendahnya total flavonoid. Flavonoid memiliki fungsi penting lainnya, diantarannya anti inflamasi, antialergi, dan anti kanker (Franyoto, et al 2018). Penlitian yang dilakukan oleh Banobe CO dan kawan-kawan menyimpulkan, bahawa antioksidan terbesar pada formulasi D2:C2 dimana kandungan kedelai lebih banyak yaitu 70% dari pada biji kecipir yaitu 30%, dan total flavonoid terbesar adalah formulasi kedelai.…”

Section: Reaksi Dengan Adanya Antioksidanunclassified

Potensi Antioksidan Kedelai (Glycine Max L) Terhadap Penangkapan Radikal Bebas

Pratama¹,

Busman²

2020

jiskh

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Radikal bebas merupakan molekul yang memiliki sifat tidak stabil dan reaktif, dikarenakan memiliki satu atau lebih elektron yang tidak berpasangan. Radikal bebas dapat menyerang senyawa yang rentan seperti, lipid dan protein, yang akhirnya akan menyebabkan penyakit berbahaya. Radikal bebas mengancam bagi kesehatan tubuh dikarenakan sifatnya yang reaktif dan tidak stabil, karna ketidakstabilannya, radikal bebas bereaksi dengan molekul yang paling dekat setelah masuk kedalam tubuh, dan menghasilkan radikal bebas lainnya, dan akhirnya menjadi reaksi berantai yang dapat mengancam kesehatan tubuh. Kedelai (Glycine max L) memiliki senyawa antioksidan yang dapat bereaksi dengan radikal bebas dan menghentikan laju radikal bebas untuk bereaksi dengan molekul dalam tubuh, yakni isoflavon dan senyawa lainnya, seperti protein, lemak, dan vitain A,C dan D. Kedelai (Glycine max L) terbukti berperan penting pada penyembuhan atau penghambatan penyakit yang disebabkan oleh radikal bebas, serta antioksidan yang terkandung yaitu isoflavon yang dikonsumsi teratur dapat melindungi tubuh dari radikal bebas.

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Total flavonoid content and formulation antioxidant cream stem of jatropha multifida l.

Cited by 4 publications

References 11 publications

Natural Deep Eutectic Solvents as a Novel Bio-Based Matrix for Ready-to-Use Natural Antioxidants-Enriched Ingredients: Extraction and Formulation Optimization

Natural Deep Eutectic Solvents as a Novel Bio-Based Matrix for Ready-to-Use Natural Antioxidants-Enriched Ingredients: Extraction and Formulation Optimization

Biological activities: anti-infectious, antioxidant and healing of the vegetable species Jatropha multifida

Potensi Antioksidan Kedelai (Glycine Max L) Terhadap Penangkapan Radikal Bebas

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