Total intravenous anesthesia for evacuation of a hydatidiform mole and termination of pregnancy in a patient with thyrotoxicosis

Thyroid Hormone Levels and Its Relationship with Human Chorionic Gonadotropin in Patients with Hydatidiform Mole

“…Hydatidiform mole is the most common form of gestational trophoblastic disease that originates from the placenta and includes complete and partial site trophoblastic tumors [19]. Clinical hyperthyroidism is relatively common, occurring in about 1 in 100 pregnant woman.…”

Evaluation of thyroid functions in molar pregnancies

“…Literatürde, ciddi hipertiroidi komplikasyonları ile karşılaşılan molar gebelik olguları ile karşılaşılmaktadır. Hiç akıldan çıkarılmamalıdır ki, hipertiroidi semptomlarının gözlendiği GTH olgularında anestezik indüksiyon tiroid fırtınasını indükleyebileceğinden, anestezi öncesinde profilaktik olarak beta-adrenerjik bloke edici ajanlar uygulanmalıdır (21)(22)(23). Tiroid fırtınası; hipertermi, deliryum, konvülsiyon, taşiaritmi, yüksek çıkışlı kalp yetmezliği veya kardiyovasküler kollaps ile seyreden bir durumdur ve kontrol altına alınamadığında ölümcül seyredebilir (24).…”

Trophoblastic Hyperthyroidism and Its Perioperative Concerns

“…Its levels are high in the first trimester of pregnancy. It shares some structural similarity with TSH [26,27] (fig6). It is composed of alpha and beta subunits, non covalently linked.…”

“…Clinical hyperthyroidism is found in approximately 5% of women with a hydatidiform mole [26]. Clinical thyrotoxicosis is rare in molar pregnancy [45].…”

“…E. Erturk et al reported the anaesthetic management of a 25 year old woman having a hydatidiform mole with hyperthyroidism using TIVA technique with propofol, remifentanil and esmolol infusion for controlling sympathetic hyperactivity during surgery [26].…”