Total Phenolic Content, Flavonoid Concentrations and Antioxidant Activity, of The Whole Plant and Plant Parts Extracts fromTeucrium MontanumL. Var.Montanum, F.Supinum(L.) Reichenb

Stanković, Milan; Nićiforović, Neda; Topuzović, Marina; Solujić, Slavica

doi:10.5504/bbeq.2011.0020

Cited by 116 publications

(85 citation statements)

References 23 publications

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“…Teucrium chamedrys and T. montanum are very rich in phenolic compounds with very strong biological activity and antioxidative effects (Č anadanović- Brunet et al 2006;Ozgen et al 2006;Gursoy and Tepe 2009;Stanković et al 2010;Stanković et al 2011b). Stankovic et al (2011a) reported that extracts from different Teucrium species caused cytotoxicity and induced apoptosis in human HCT-116 cells (human colon cancer cell line), hence they could be considered suitable natural anticancer products.…”

Section: Discussionmentioning

confidence: 99%

Comparative study of genotoxicity and antimutagenicity of methanolic extracts from Teucrium chamaedrys and Teucrium montanum in human lymphocytes using micronucleus assay

et al. 2013

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Since Teucrium chamaedrys and Teucrium montanum are the most popular plants used in the treatment of many diseases, we evaluated genotoxic potential of their methanolic extracts on cultured human peripheral blood lymphocytes (PBLs) using cytokinesis-block micronucleus (MN) assay. Cultures were treated with four concentrations of both plants (125, 250, 500 and 1,000 lg/ml), both separately and in combination with mitomycin C (MMC). The results revealed that extract of T. chamaedrys administered at the tested concentrations did not significantly affect the mean MN frequency in comparison to untreated cells. Methanolic extract of T. montanum increased the mean MN frequency in PBL at the tested concentrations, but significantly only at the concentration of 1,000 lg/ml. In all tested concentrations, the extract of T. chamaedrys significantly reduced the MMC-induced MN frequency, in a dose dependent manner (r = -0.687, p \ 0.01). The extract of T. montanum decreased the MMC-induced MN frequency at the tested concentrations, but statistically only at 125 lg/ ml. Both extracts administered alone did not significantly affect the nuclear division index (NDI) at the tested concentrations. In the combined treatments with MMC, the extract obtained from T. chamaedrys in the concentrations of 500 and 1,000 lg/ml significantly decreased NDI values in comparison to MMC-treated cells alone, while the extract of T. montanum significantly decreased NDI at all tested concentrations. Both extracts nonsignificantly decreased NDI at all tested concentrations in comparison to untreated cells. Our results suggest the important function of T. chamaedrys extract in cancer therapy, this methanolic extract may prevent genotoxic effects of chemotherapy in PBLs.

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Section: Discussionmentioning

confidence: 99%

Comparative study of genotoxicity and antimutagenicity of methanolic extracts from Teucrium chamaedrys and Teucrium montanum in human lymphocytes using micronucleus assay

et al. 2013

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“…Total polyphenol content in green tea samples measured by Chrpova et al [29] varied between 63.7 and 112.8 mg equivalent of gallic acid per gram of dried leaves. In turn, in the study by Stankovic et al [30], the values for total phenolic content of green extracts ranged from 16.02 to 233.68 mg GA g -1 and were dependent on the solvent used for the extraction. Also, the origin and type of tea affect the polyphenol content in extracts.…”

Section: Discussionmentioning

confidence: 99%

Effect of addition of plant extracts on the durability and sensory properties of oat flake cookies

Żbikowska

Kozłowska

Półtorak

et al. 2018

J Therm Anal Calorim

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Fragile cookies are one of the most popular high-fat cereal products. Products of this type with added oat flakes may be labeled with a nutrition claim and may be included in functional foods. Fat from oat flakes and which is a recipe ingredient of cookies undergoes degradation during storage which leads to the formation of harmful oxidation products and sensory changes in products. The aim of this study was to determine the effect of green tea extracts (GT), blackcurrant (BC) seeds and nettles (N) on the rate of fat degradation in cookies with oat flakes and their sensory properties. In this work, the antioxidant effect of natural extracts antioxidant on oxidative stability of fat extracted from cookies was evaluated by differential scanning calorimetry (DSC) and by peroxide value, anisidine value and specific UV extinctions (K value). Moreover, cookies were subjected to sensory analysis and to instrumental measurements of color changes. The extracts used in the study had an influence on the rate of fat oxidation changes in cookies after baking and also during 3 months of storage. The most effective fat degradation inhibitor was the extract with GT in 1% addition, while the most unfavorable change was observed in fat with the lowest addition of N extract (0.5%). It was observed that the applied plant extracts did not significantly reduce the sensory properties of the products. The most desirable products were the cookies with 1% GT extract and those with the highest proportion of blackcurrant seed extract (1.5%).

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“…Analyzing the in vitro radical scavenging properties of S. rigidum, it may be noted that the aqueous extract has the highest DPPH radical neutralizing capacity. In previous studies of antioxidants in case of the used solvents, aqueous extracts have shown good activity [22].…”

Section: Discussionmentioning

confidence: 99%

“…The concentration of flavonoids was determined using a spectrophotometric method [22]. The sample contained 1 ml of methanolic solution of the extract in the concentration of 1 mg/ml and 1 ml of 2% AlCl 3 (Fluka Chemie, Switzerland) solution dissolved in methanol.…”

Section: Determination Of Flavonoid Concentrations In the Plant Extractsmentioning

confidence: 99%

In vitrobiological activity of secondary metabolites fromSeseli rigidumWaldst. et Kit. (Apiaceae)

Jakovljević¹,

Vasić²,

Stanković³

et al. 2015

Acta Biologica Hungarica

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The antioxidant, antimicrobial activity, total phenolic content and flavonoid concentration of Seseli rigidum Waldst. et Kit. were evaluated. Five different extracts of the aboveground plant parts were obtained by extraction with distilled water, methanol, acetone, ethyl acetate and petroleum ether. Total phenols were determined using the Folin-Ciocalteu's reagent, with the highest values obtained in the acetone extract (102.13 mg GAE/g). The concentration of flavonoids, determined by using a spectrophotometric method with aluminum chloride and expressed in terms of rutin equivalent, was also highest in the acetone extracts (291.58 mg RUE/g). The antioxidant activity was determined in vitro using DPPH reagent. The greatest antioxidant activity was expressed in the aqueous extract (46.15 µg/ml). In vitro antimicrobial activities were determined using a microdilution analysis method; minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) were determined. Methanolic extract had the greatest influence on bacilli (MIC at 0.0391 mg/ml), but the best antimicrobial effect had acetone and ethyl acetate extracts considering their broad impact on bacteria. According to our research, S. rigidum can be regarded as promising candidate for natural plant source with high value of biological compounds.

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Total Phenolic Content, Flavonoid Concentrations and Antioxidant Activity, of The Whole Plant and Plant Parts Extracts fromTeucrium MontanumL. Var.Montanum, F.Supinum(L.) Reichenb

Cited by 116 publications

References 23 publications

Comparative study of genotoxicity and antimutagenicity of methanolic extracts from Teucrium chamaedrys and Teucrium montanum in human lymphocytes using micronucleus assay

Comparative study of genotoxicity and antimutagenicity of methanolic extracts from Teucrium chamaedrys and Teucrium montanum in human lymphocytes using micronucleus assay

Effect of addition of plant extracts on the durability and sensory properties of oat flake cookies

In vitrobiological activity of secondary metabolites fromSeseli rigidumWaldst. et Kit. (Apiaceae)

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