Total Protein Concentration in Selectively Collected Secretions from the Middle and Inferior Meatus of the Nose

Sueno, Kohei; Nakaima, Norihide; Shingaki, Kaoru; Ura, Masaharu; Noda, Yutaka; Kosugi, Tadayoshi; Eichner, H

doi:10.1016/s0385-8146(86)80040-2

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Chemical Barrier Proteins In Human Body Fluids1

Nasal Secretion As a Valuable Source Of Potential Biomarkers1

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2022

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“…The production rate and the protein concentration of nasal secretion show high variability. The protein concentration varies between 0.8 mg/mL and 32.7 mg/mL [ 128 , 129 ]. Nasal secretion contains AMPs such as lactotransferrin, lysozyme-C [ 130 ], and immunoglobulin molecules [ 131 ].…”

Section: Chemical Barrier Proteins In Human Body Fluidsmentioning

confidence: 99%

Chemical Barrier Proteins in Human Body Fluids

et al. 2022

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Chemical barriers are composed of those sites of the human body where potential pathogens can contact the host cells. A chemical barrier is made up by different proteins that are part of the antimicrobial and immunomodulatory protein/peptide (AMP) family. Proteins of the AMP family exert antibacterial, antiviral, and/or antifungal activity and can modulate the immune system. Besides these proteins, a wide range of proteases and protease inhibitors can also be found in the chemical barriers maintaining a proteolytic balance in the host and/or the pathogens. In this review, we aimed to identify the chemical barrier components in nine human body fluids. The interaction networks of the chemical barrier proteins in each examined body fluid were generated as well.

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Section: Chemical Barrier Proteins In Human Body Fluidsmentioning

confidence: 99%

Chemical Barrier Proteins in Human Body Fluids

et al. 2022

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“…Protein amounts produced between 0.8 and 32.7 mg/ml were observed depending on the collection methods [103,104]. Nasal discharge contains a lot of antimicrobial proteins; such as lysozyme-C, lactotransferrin, several types of defensins [105], also in addition to components of the adaptive immune system, such as immunoglobulins [106].…”

Section: Nasal Secretion As a Valuable Source Of Potential Biomarkersmentioning

confidence: 99%