(1) Background: Studies on women with disabilities (WwD) are rare and tend to reveal certain representation patterns. This study aims to understand how and to what extent WwD and chronic diseases are deemed newsworthy in the Portuguese public news TV station RTP1 primetime news program. Feminist disability, standpoint, agenda-setting, and framing theories are used alongside the concept of intersectionality. (2) Methods: A mixed-method approach is adopted, combining quantitative content analysis of all broadcasted news in January 2020 (n = 704), and qualitative discourse analysis of news items on PwD (n = 5). (3) Results: The results reveal that disability is a reduced issue in Telejornal’s agenda. PwD, in general, are often portrayed in secondary roles and without a voice. The protagonists of news stories about disability or persons with disabilities are predominantly women without disabilities, occupying traditional roles as caregivers (mothers, nurses), while men are more often portrayed as public agents. Discourse analysis deepens understanding by uncovering the prevalence of negative news values and a problem-centred framing, often associated with negativity, rather than presenting solutions. (4) Conclusions: Consequently, WwD were found to be deprived of news representation with a more positive or ‘normal’ focus and an intersectional approach reveals a lack of inclusion, with the few existing news tending to focus on exclusion issues, portraying only white Portuguese women. This study underscores the urgent need for a more equitable approach in media representation, recognising the diversity and positive contributions of WwD to promote an inclusive narrative.