Toward High-Performance Coatings for Biomedical Devices: Study on Plasma-Deposited Fluorocarbon Films and Ageing in PBS

Abstract

High performance coatings tailored to medical devices represent a recognised approach to modulate surface properties. Plasma-deposited fluorocarbon films have been proposed as a potential stent coating. Previous studies have shown promising adhesion properties: the 35 nm-thick film sustained plastic deformation up to 25% such as induced during the clinical implantation. In this study, the compositional and morphological changes of plasma-deposited fluorocarbon films were examined during ageing in a pseudo-physiological medium, a phosphate buffer solution (PBS), by angle-resolved XPS, FT-IR data and AFM images. The evolution of the ageing process is discussed: defluorination and crosslinking yielded an oxidized protective top layer onto the films, which showed further degradation.

Investigation of the Performance of Barrel Atmospheric Plasma Source for the Deposition of Fluorocarbon Coating onto Silicone Polymer Particles

“…A typical survey spectrum is shown in Figure 7. As expected the elements F and C were detected along with O probably due to oxidation of the fluorocarbon coating due to reactions with atmospheric oxygen [19]. The theoretical elemental composition calculated from the chemical formula of the monomer based on the relative concentration of the elements in the 1H, 1H, 2H -Perfluoro -1 -Decene molecule is 37% carbon, 63% fluorine giving an F:C ratio of 1.7:1.…”

Effects of different polyaniline emeraldine compositions in electrodepositing ginsenoside encapsulated poly(lactic‐co‐glycolic acid) microcapsules coating: Physicochemical characterization and in vitro evaluation

“…These tests were done in triplicate at 37°C in a shaking incubator. The PBS was chosen in this study due to its similarity in ionic strength, degree of acidity, and composition with the human blood plasma (Holvoet, Chevallier, Turgeon, & Mantovani, ). The test was conducted for a month by refreshing the PBS every week and collecting the aged coated metals on the final day of immersion.…”

Protective applications of vacuum-deposited perfluoropolymer films

“…The compositional and morphological changes of the PFP films were examined during ageing in a pseudophysiological medium, a phosphate buffer solution, by angle-resolved XPS, FTIR and AFM. The evolution of the ageing process is described as follows: defluorination and crosslinking yielded an oxidized protective top layer onto the films, which shows further degradation [14]. The effect of 25% plastic deformation on stability and ageing characteristics of the PFP coating were also verified.…”