Abstract:The development of a very-compact DNA sequencer instrument based on Single Photon Avalanche Diode (SPAD) for microchip electrophoresis is here reported. The planar epitaxial SPAD combines the typical advantages of microelectronic devices with high sensitivity. We present a miniaturized system based on a custom array of SPAD, purposely designed to be compatible with Amersham Biosciences commercial markers. This system is the first example of very compact, ultra-sensitive, portable and low cost DNA sequencer. It… Show more
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