The development and transformation of the ecological environment is an important content and future indicator of global environmental change. At the same time, people of all countries are affected by comprehensive human factors such as local and local cultural industries and humanistic thoughts while jointly protecting the environment. This paper studies the coupling relationship between the development of village cultural industry and ecological environment changes and comprehensively considers the aspects of detecting regional ecological environment changes, optimizing cultural industry facilities, coordinating regional sustainable development, and constructing regional ecological security patterns in the context of rural revitalization. The results showed that the vegetation or forest coverage increased by 9.2%, 17.4%, 28.1% and 30.5% respectively under the cultural industry protection levels of 2-5. The air pollution index decreased by 11.2%, 17.9%, 25.2% and 30.3% respectively, and the pollution of river water resources decreased by 4.1%, 6.6%, 8.9% and 11.1% respectively. The comprehensive ecological environment development index increased by 9.43%, 17.41%, 28.59%, 30.48%, 31.61%, 33.22%, 34.80%, 35.71% and 36.27% respectively under the cultural industry development level of 2-10. Overall, the cultural relics protection strategy of the village cultural industry under the background of rural revitalization has significantly promoted the comprehensive ecological environment in the entire planned area.