Towards the synthesis of N-heterocycle containing BINOL-phosphoramidites

Recsei, Carl; McErlean, Christopher S. P.

doi:10.1016/j.tetasy.2009.12.019

Cited by 8 publications

(2 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At lower temperature (50 °C) the carbonylation reaction is accompanied by deiodination. The corresponding product 8′ was identified in a mixture of 10 a : 8′ (53:47), as determined by 1 H NMR but not isolated in analytically pure form (Scheme ).…”

Section: Resultsmentioning

confidence: 99%

Facile, High‐Yielding Synthesis of 4‐Functionalised 1,2,3‐Triazoles via Amino‐ and Aryloxycarbonylation

et al. 2020

View full text Add to dashboard Cite

4‐Iodo‐1,2,3‐triazoles were synthesised via azide‐alkyne cycloaddition of alkynyl Grignard reagent and benzyl azide followed by iodination reaction. The aminocarbonylation and aryloxycarbonylation of 4‐iodo‐1,2,3‐triazoles were carried out in the presence of various N‐ and O‐nucleophiles, resulting in the corresponding triazole‐based 4‐carboxamides and 4‐esters, respectively. Both high‐yielding reactions were carried out under mild conditions (atmospheric CO pressure, 70 °C).

show abstract

Section: Resultsmentioning

confidence: 99%

Facile, High‐Yielding Synthesis of 4‐Functionalised 1,2,3‐Triazoles via Amino‐ and Aryloxycarbonylation

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The use of phosphorus(III) in this catalytic role has precedent in iodolactonizations . To this end, we recently reported the development of a library of N -heterocycle-substituted phosphoramidites. , The required balance between oxidative stability versus catalytic activity led us to settle upon the 2,4,5-trichlorophenyltriazole (TCPT)-flanked catalyst 8 for this work (Figure ).…”

Section: Introductionmentioning

confidence: 99%