Toxicidade e atividade antibacteriana de plantas medicinais utilizadas no tratamento de doenças respiratórias: revisão integrativa

Oliveira, Maria Clara Borges de; Cruz, Celsa Karolayne Silva; Rocha, Gabriel Mauriz de Moura; Brito, Mauro Gustavo Amaral; Oliveira, Guilherme Antônio Lopes de

doi:10.33448/rsd-v9i9.7169

Cited by 3 publications

(1 citation statement)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Nos ensaios in vitro são inúmeros os bioensaios utilizados para a avaliação dos efeitos tóxicos das espécies vegetais. Já nos ensaios in vivo, com animais de laboratório são feitos os ensaios de toxicidade aguda e crônica 16 .…”

unclassified

Estudo experimental in vivo e in vitro de plantas medicinais nos processos de embriotoxicidade e teratogenicidade

Santos

Volejo

2021

Saúde e meio ambient.: rev. interdisciplin.

View full text Add to dashboard Cite

Este trabalho tem como objetivo contribuir na compilação de artigos científicos sobre as plantas medicinais que possuem efeitos embriotóxicos e teratogênicos comprovados através de testes experimentais in vivo e in vitro. Foi realizado um levantamento nas bases de dados Medline, Pubmed, Web of Science, Cochrane, Biblioteca virtual em saúde, Lilacs e Scielo com os descritores, “Medicinal plants, embryotoxicity”; “Medicinal plants, Teratogenic effects”; “Medicinal plants, teratogenicity” e seus correspondentes em português: “Plantas medicinais, embriotoxicidade”; “Plantas medicinais, efeitos Teratogênicos”; “Plantas Medicinais Teratogenicidade”. Oito artigos de ensaios in vivo e quatro de in vitro e um que apresenta os dois ensaios, preencheram os critérios de inclusão e exclusão e foram selecionados para esta revisão. Destes, cinco foram realizados na América, um na Europa, três na África e dois na Ásia. Na maioria dos estudos in vivo o extrato da planta foi injetado no animal, observando assim seus efeitos. A partir deste estudo, foi verificado que as plantas podem apresentar algum tipo de efeito no processo embrionário, portanto, o consumo durante o estado gravidico deve ser avaliado por um profissional da área. Palavras-chave: Gestação. Planta medicinal. Embriotoxicidade. Teratogênico.

show abstract

unclassified

Estudo experimental in vivo e in vitro de plantas medicinais nos processos de embriotoxicidade e teratogenicidade

Santos

Volejo

2021

Saúde e meio ambient.: rev. interdisciplin.

View full text Add to dashboard Cite

show abstract

Asteraceae Family Species used as Medicinal Plants in the Treatment of Respiratory Diseases in the State of Amapá, Amazon – Brazil: A Systematic Review

Pantoja,

Oliveira

2023

RGSA

View full text Add to dashboard Cite

Purpose: To conduct a survey of species of the Asteraceae family used to treat respiratory diseases in the state of Amapá. Theoretical framework: The use of plants is part of popular Brazilian phytotherapy. Brazilian authorities have been regulating public policies focused on medicinal plants. Ethnobotanical and ethnofarmacological studies point to traditional knowledge about Asteraceae plants in the treatment of respiratory problems in the state of Amapá. Method/design/approach: The review method was used, and scientific databases such as articles, theses, dissertations, and monographs were used as sources. Portuguese keywords such as "Medicinal Plants," "Respiratory System," "Ethnobotany," "Ethnofarmacology," and "State of Amapá" were used, as well as their English equivalents. Studies conducted in the Amapá territory from 2001 to 2021 were selected. Results and conclusion: Eight species of Asteraceae indicated for respiratory pathologies were found, three of which are native to Brazil. There is a predominant use of herbaceous plants, leaves, and teas, with influenza being the most common illness treated. A. triplinervis (japana) stood out, as it was cited in five studies and is indicated for several diseases. Japana has relevant chemical and pharmacological studies that validate its ethnofarmacological use. Research implications: The study is relevant for the valorization of traditional knowledge regarding the traditional knowledge and biodiversity of the Brazilian medicinal flora. Originality/value: This research provides relevant information for the scientific community, as it provides data on popularly used medicinal plants that can serve as a basis for future chemical and pharmacological studies with the species found.

show abstract

Mass Spectrometric Identification of Licania rigida Benth Leaf Extracts and Evaluation of Their Therapeutic Effects on Lipopolysaccharide-Induced Inflammatory Response

et al. 2022

View full text Add to dashboard Cite

Licania rigida Benth has been evaluated as an alternative drug to treat diseases associated with inflammatory processes. This study evaluated the anti-inflammatory effects of aqueous and hydroalcoholic leaf extracts of L. rigida with inflammation induced by lipopolysaccharides in in vitro and in vivo inflammation models. The phytochemical profile of the extracts, analyzed by ultra-fast liquid chromatography coupled with tandem mass spectrometry, revealed the presence of gallic and ellagic acids in both extracts, whereas isovitexin, ferulate, bulky amino acids (e.g., phenylalanine), pheophorbide, lactic acid, and pyridoxine were detected in the hydroalcoholic extract. The extracts displayed the ability to modulate in vitro and in vivo inflammatory responses, reducing approximately 50% of pro-inflammatory cytokine secretion (TNF-α, IL-1β, and IL-6), and inhibiting both NO production and leukocyte migration by approximately 30 and 40% at 100 and 500 µg/mL, respectively. Overall, the results highlight and identify, for the first time, the ability of L. rigida leaf extract to modulate inflammatory processes. These data suggest that the leaf extracts of this plant have potential in the development of herbal formulations for the treatment of inflammation.

show abstract

Toxicidade e atividade antibacteriana de plantas medicinais utilizadas no tratamento de doenças respiratórias: revisão integrativa

Cited by 3 publications

References 35 publications

Estudo experimental in vivo e in vitro de plantas medicinais nos processos de embriotoxicidade e teratogenicidade

Estudo experimental in vivo e in vitro de plantas medicinais nos processos de embriotoxicidade e teratogenicidade

Asteraceae Family Species used as Medicinal Plants in the Treatment of Respiratory Diseases in the State of Amapá, Amazon – Brazil: A Systematic Review

Mass Spectrometric Identification of Licania rigida Benth Leaf Extracts and Evaluation of Their Therapeutic Effects on Lipopolysaccharide-Induced Inflammatory Response

Contact Info

Product

Resources

About