Tracheal cancer in Denmark: a nationwide study

Licht, Peter B.; Friis, Søren; Pettersson, Gösta

doi:10.1016/s1010-7940(01)00597-8

Cited by 115 publications

(132 citation statements)

References 22 publications

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“…6 Similar proportions were found in epidemiologic studies from Denmark and Finland. 7,8 The discrepancy between reported ratios of surgical clinics and these epidemiologic studies may be partly based on patient selection. However, some authors suspected a lack of knowledge and a nihilistic attitude toward the treatment of tracheal malignancies.…”

mentioning

confidence: 99%

Undertreatment of Tracheal Carcinoma: Multidisciplinary Audit of Epidemiologic Data

et al. 2008

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National epidemiologic data were examined to determine the eligibility for curative therapy in tracheal carcinoma. An expert audit of primary tracheal carcinomas registered from 2000 to 2005 with the Netherlands Cancer Registry (NCR) included blinded patient data and radiographic review to assess diagnosis and resectability. Actual treatment was compared with the opinions of a multidisciplinary panel (Radboud panel) and a second reviewer. Of 101 NCR-registered primary tracheal carcinomas, the Radboud panel diagnosis was metastatic disease or local extension of adjacent tumors in 34. Seventeen cases were excluded for missing data. In 50 cases confirmed by panel and a second reviewer, actual treatment consisted of surgery in 12 (24%), radiotherapy in 29 (58%), endobronchial treatment in 6 (12%), and observation in 3 (6%). Both panel and second reviewer identified 16 additional surgical candidates, a total of 28 (56%) of 50. Treatment recommendations of panel and second reviewer disagreed in four cases (8%). One-third of NCR-registered primary tracheal carcinomas were misclassified nontracheal primary tumors involving the trachea. A majority of cases meeting audit criteria for diagnosis and surgical resection was treated with other modalities. Interreviewer disagreement was small. The audit of a national cancer registry suggests that incorrect diagnosis and undertreatment are common in rare airway tumors.Primary malignancies of the trachea are rare and challenging tumors. Surgical resection of the involved tracheal segment is the treatment of choice, and long-term diseasefree survival has been reported after tracheal resection.

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confidence: 99%

Undertreatment of Tracheal Carcinoma: Multidisciplinary Audit of Epidemiologic Data

et al. 2008

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“…Similarly, a more recent national study conducted in Denmark has reported a 52% 5-year survival rate in patients undergoing resection for adenoid cystic tumours compared to 33% in non surgically treated patients [33].…”

Section: Tracheal Resectionsmentioning

confidence: 91%

“…Overall periop-could be due to the limited numbers and the not systematically reported lymphadenectomy. Conversely, some authors [33,34] have shown a significant correlation between staging and survival in patients undergoing surgery.…”

Section: Tracheal Resectionsmentioning

confidence: 97%

“…When considering tracheal resection for tumour, epidemiological studies [32][33][34] show that in most patients the malignant disease is locally advanced at the time of diagnosis and therefore it is treated with non-surgical modalities. The possibility of undergoing complete resection significantly improves the prognosis of these patients.…”

Section: Tracheal Resectionsmentioning

confidence: 99%

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Tracheal surgery

D’Andrilli

Rendina

Venuta

2016

Monaldi Arch Chest Dis

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Surgical resection and reconstruction of the trachea can be performed both for benign and malignant diseases. The main indications for surgery include inflammatory (generally post-intubation), congenital or post-traumatic stenoses, degenerative lesions, benign or malignant neoplasms. Success can be pursued only by accurate patient selection and timing, meticulous surgical techniques, careful follow up and, when required, multidisciplinary cooperation. Although surgical resection has now become part of our surgical practice, other treatment modalities are approaching a new clinical application era, in particular tracheal transplantation and bioengineering. These new techniques will certainly offer, in the near future, improved chances to treat difficult cases.

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“…Yapılan epidemiyolojik çalışmalara göre hastaların %59'u erkektir ve bunlarında %73'ü sigara içmek-tedir. 3,4 Tanıları oldukça zordur ve rutin radyolojik tetkikler de çoğu zaman tanıda yetersiz kalır. Esas semptomları dispneyi takiben diğer üst hava yolu tıkanıklığı semptomlarıdır.…”

Section: Introductionunclassified

The squamous cell carcinoma case that received long-term COPD treatment

Türk¹

2013

Dicle Med J

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Primary tracheal tumors are rare, and composed of various benign and malignant pathologies. They often can simulate obstructive pulmonary diseases, such as asthma and chronic obstructive pulmonary disease, and patients with malign tracheal tumors sometimes undergo long-term treatment for such diseases, without any improvement. Therefore, these tumors should be included in the differential diagnosis in patients presenting tracheobronchial tree obstruction. We present a squamous cell endotracheal carcinoma case that had received treatment with a diagnosis of chronic obstructive pulmonary disease for a long time. The recent increase in symptoms had been thought to be due to an exacerbation of the disorder but the bronchoscopy performed after 3 months of no improvement revealed an endotracheal mass lesion. Full recovery was obtained with bronchoscopic resection of the tumor.Key words: Endotracheal tumor, chronic obstructive pulmonary disease, squamous cell carcinoma ÖZETÇeşitli benign ve malign patolojilerden oluşan primer trakeal tümörler oldukça nadir görülürler. Malign trakeal tü-mörlü hastalar bazen astma ve kronik obstrüktif akciğer hastalığı (KOAH) gibi tıkanıklık yapan akciğer hastalıkla-rını taklit edebilirler ve herhangi bir iyileşme olmaksızın uzun süre bu tür hastalıkların tedavisini alabilirler. Bu nedenle bu tümörler trakeobronşial ağaç tıkanıklığı bulguları gösteren hastaların ayırıcı tanısına dahil edilmelidirler. Bu olgu sunumunda, uzun süre kronik obstrüktif akciğer hastalığı tanısı nedeniyle tedavi gören ve son zamanlarda artan şikayetleri hastalığının alevlenmesi olarak değer-lendirilen, yaklaşık 3 ay takiplerinde düzelme olmayınca bronkoskopik olarak endotrakeal kitle lezyonu saptanarak tümörün bronkoskopik rezeksiyonu sonrası tam klinik iyileşme gözlenen skuamoz hücreli endotrakeal karsinom olgusu sunulmuştur.Anahtar kelimeler: Endotrakeal tümör, kronik obstrüktif akciğer hastalığı, skuamöz hücreli karsinom GİRİŞPrimer trakeal tümörler çok nadir görülür ve tüm malignitelerin %0,1-0,4'ünü oluşturur.1 Malign formlarının %80-90'ı ileri yaşlarda görülür.2 Skuamöz hücreli tümörler ve adenoid kistik karsinomalar erişkin trakea tümörlerinin 2/3'ünü oluşturur. Skuamöz hücreli karsinom için ortalama görülme yaşı 60 iken adenoid kistik karsinomalar için 50 yaş altıdır. Yapılan epidemiyolojik çalışmalara göre hastaların %59'u erkektir ve bunlarında %73'ü sigara içmek-tedir.3,4 Tanıları oldukça zordur ve rutin radyolojik tetkikler de çoğu zaman tanıda yetersiz kalır. Esas semptomları dispneyi takiben diğer üst hava yolu tıkanıklığı semptomlarıdır.3 KOAH'da da hava yolları lümeninin sekresyonla daralması, hava yolu duvarında kalınlaşma, intraparankimal hava yollarını çevreleyen akciğer dokusunun elastik geri tepme basıncında azalmaya bağlı kollaps gibi nedenlerle hava akımında kısıtlanma olur.5 Trakeal tümörler-de üst hava yolları tıkanıklığına sebep olarak, efor dispnesi ve wheezing olan hastalarda ayırıcı tanıya gidilirken çekilen posteroanterior akciğer grafisinin normal olarak değerlendirilmesi ü...

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Tracheal cancer in Denmark: a nationwide study

Cited by 115 publications

References 22 publications

Undertreatment of Tracheal Carcinoma: Multidisciplinary Audit of Epidemiologic Data

Undertreatment of Tracheal Carcinoma: Multidisciplinary Audit of Epidemiologic Data

Tracheal surgery

The squamous cell carcinoma case that received long-term COPD treatment

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