“…This decrease in the exogenous pneumonia rate could be due to the fact that CTSS avoids direct manipulations of the aspiration catheter, as it is protected by a plastic envelope. Nevertheless, in two recent randomised studies, no significant differences were found between the patients suctioning with CTSS or OTSS in terms of either total VAP incidence or exogenous VAP incidence [104,105]. Thus, the evidence does not support the routine use of CTSS for prevention of VAP.…”