Track reconstruction with the silicon strip tracker of the proton CT Phase 2 scanner

Zatserklyaniy, A.; Johnson, R. P.; Macafee, S.; Plautz, Tia; Sadrozinski, H. F-W.; Bashkirov, V.; Hurley, Ford; Schulte, R.; Vence, Nicholas; Giacometti, Valentina

doi:10.1109/nssmic.2014.7430749

Cited by 3 publications

(4 citation statements)

References 5 publications

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“…The Geant4 simulation correctly reproduced the drop in tracking efficiencies due to the vertical gaps in sensitivity between individual SSDs also seen in the experimental profiles. One should note that the missing coordinates due to the gaps were reconstructed based on the information from the other tracking planes and knowledge of the gap coordinates …”

Section: Resultsmentioning

confidence: 99%

Software platform for simulation of a prototype proton CT scanner

et al. 2017

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Purpose: Proton computed tomography (pCT) is a promising imaging technique to substitute or at least complement x-ray CT for more accurate proton therapy treatment planning as it allows calculating directly proton relative stopping power from proton energy loss measurements. A proton CT scanner with a silicon-based particle tracking system and a five-stage scintillating energy detector has been completed. In parallel a modular software platform was developed to characterize the performance of the proposed pCT. Method: The modular pCT software platform consists of (1) a Geant4-based simulation modeling the Loma Linda proton therapy beam line and the prototype proton CT scanner, (2) water equivalent path length (WEPL) calibration of the scintillating energy detector, and (3) image reconstruction algorithm for the reconstruction of the relative stopping power (RSP) of the scanned object. In this work, each component of the modular pCT software platform is described and validated with respect to experimental data and benchmarked against theoretical predictions. In particular, the RSP reconstruction was validated with both experimental scans, water column measurements, and theoretical calculations. Results: The results show that the pCT software platform accurately reproduces the performance of the existing prototype pCT scanner with a RSP agreement between experimental and simulated values to better than 1.5%. Conclusions: The validated platform is a versatile tool for clinical proton CT performance and application studies in a virtual setting. The platform is flexible and can be modified to simulate not yet existing versions of pCT scanners and higher proton energies than those currently clinically available.

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Section: Resultsmentioning

confidence: 99%

Software platform for simulation of a prototype proton CT scanner

et al. 2017

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“…In many cases those events can be recovered as follows [16]. In T layers the gaps are parallel to the strips.…”

Section: Tracking Detectormentioning

confidence: 99%

“…Prior to image reconstruction the raw data are preprocessed to calculate the coordinates of the tracker hits, to associate the hits with proton tracks [16], and to derive the WEPL from the 5-stage detector digitizations according to the calibration described in Section IV.…”

Section: Image Reconstructionmentioning

confidence: 99%

A Fast Experimental Scanner for Proton CT: Technical Performance and First Experience With Phantom Scans

Johnson

Bashkirov

DeWitt

et al. 2016

IEEE Trans. Nucl. Sci.

103

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We report on the design, fabrication, and first tests of a tomographic scanner developed for proton computed tomography (pCT) of head-sized objects. After extensive preclinical testing, pCT is intended to be employed in support of proton therapy treatment planning and pre-treatment verification in patients undergoing particle-beam therapy. The scanner consists of two silicon-strip telescopes that track individual protons before and after the phantom, and a novel multistage scintillation detector that measures a combination of the residual energy and range of the proton, from which we derive the water equivalent path length (WEPL) of the protons in the scanned object. The set of WEPL values and the associated paths of protons passing through the object over a 360° angular scan are processed by an iterative, parallelizable reconstruction algorithm that runs on modern GP-GPU hardware. In order to assess the performance of the scanner, we have performed tests with 200 MeV protons from the synchrotron of the Loma Linda University Medical Center and the IBA cyclotron of the Northwestern Medicine Chicago Proton Center. Our first objective was calibration of the instrument, including tracker channel maps and alignment as well as the WEPL calibration. Then we performed the first CT scans on a series of phantoms. The very high sustained rate of data acquisition, exceeding one million protons per second, allowed a full 360° scan to be completed in less than 10 minutes, and reconstruction of a CATPHAN 404 phantom verified accurate reconstruction of the proton relative stopping power in a variety of materials.

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“…Figure 3 shows a photogr boards. is an essential requirement s almost no redundancy in measurements ("hits") are otons do pass through the h are staggered from one ases those events can be recovered as follows [9]. In layers the gaps are parallel to the strips.…”

Section: Tracking Detectormentioning

confidence: 99%

Results from a pre-clinical head scanner for proton CT

Johnson

Bashkirov

Giacometti

et al. 2014

2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

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Abstract-We report on the first beam test results with our pre-clinical (Phase-II) head scanner developed for proton computed tomography (pCT). After extensive preclinical testing, pCT will be employed in support of proton therapy treatment planning and pre-treatment verification in patients undergoing treatment with particle beam therapy. The Phase-II pCT system consists of two silicon-strip telescopes that track individual protons before and after the phantom or patient, and a novel multistage scintillation detector that measures a combination of the residual energy and range of the proton, from which we derive the water equivalent path length (WEPL) of the protons in the scanned object. The set of WEPL values and associated paths of protons passing through the object over a 360° angular scan is processed by an iterative, parallelizable reconstruction algorithm that runs on modern GP-GPU hardware. In order to assess the performance of the scanner, we have performed beam tests with 200 MeV protons from the synchrotron of the Loma Linda University Medical Center. The first objective was the calibration of the instrument, including tracker channel maps and alignment as well as the WEPL calibration. Then we performed the first CT scans on a series of phantoms. The very high sustained rate of data acquisition, exceeding one million protons per second, allowed a full 360° scan to be completed in less than 10 minutes, and reconstruction of a CATPHAN 404 phantom verified accurate reconstruction of the proton relative stopping power in a variety of materials.

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Track reconstruction with the silicon strip tracker of the proton CT Phase 2 scanner

Cited by 3 publications

References 5 publications

Software platform for simulation of a prototype proton CT scanner

Software platform for simulation of a prototype proton CT scanner

A Fast Experimental Scanner for Proton CT: Technical Performance and First Experience With Phantom Scans

Results from a pre-clinical head scanner for proton CT

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